EFFECT OF OMEGA-3 FATTY ACIDS ON INFLAMMATORY MEDIATORS, INSULIN SENSIVITY AND METABOLIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES

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RASTMANESH R.; TALEBAN F.A.; KIMIAGAR SEYED MASOUD; MEHRABI YAD ELAH

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Journal: Researcher Bulletin of Medical Sciences Year:2005 | Volume:9 | Issue:5 (41) Page(s): 281-287

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Title

EFFECT OF OMEGA-3 FATTY ACIDS ON INFLAMMATORY MEDIATORS, INSULIN SENSIVITY AND METABOLIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES

Author(s)

RASTMANESH R. | TALEBAN F.A. | KIMIAGAR SEYED MASOUD | MEHRABI YAD ELAH | Issue Writer Certificate

Keywords

TYPE 2 DIABETES MELLITUSQ3

OMEGA-3 FATTY ACIDSQ4

METABOLIC CONTROLQ4

CYTOKINEQ1

ACUTE PHASE PROTEINSQ1

Abstract

Background: TYPE 2 DIABETES MELLITUS may represent a disease of the innate immune system responsible for an ongoing CYTOKINE-mediated acute phase response and fish oil may suppress inflammatory mediator. The ability of OMEGA-3 FATTY ACIDS from fish oil to suppress inflammatory mediators and and its consequent effect on glycemia, serum lipids, blood pressure and insulin sensivity was studied in a clinical trial on patients with TYPE 2 DIABETES MELLITUS.Materials and methods: A total of 26 (10 male and 16 female) were given 3000 mg OMEGA-3 FATTY ACIDS, daily, for 8 weeks. The serum level of inflammatory determinates and biochemical ultrasensors were measured by kits, and aquestionnair based on body measurement (anthropometric indexes), medical data was completed. Results: All 26 cases (10 male, 16 female) full filled the study. mean age, acquiring DM, body mass index were 52.7 9.2 years (1SD), 9 6.0 years, and 27.32 2.9 years respectively. The results of this study showed there were no significant differences in fasting blood glucose and insulin at baseline, week 4 and week 8 after supplementation despite a significant decrease in serum sialic acid triglycerides, cholesterol and blood pressure were decreased.Conclusion: A moderate dose of OMEGA-3 FATTY ACIDS did not lead to deleterious effects on glycemia control in patients with TYPE 2 DIABETES MELLITUS, with preserved beneficial capacities.

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APA: Copy

RASTMANESH, R., TALEBAN, F.A., KIMIAGAR, SEYED MASOUD, & MEHRABI, YAD ELAH. (2005). EFFECT OF OMEGA-3 FATTY ACIDS ON INFLAMMATORY MEDIATORS, INSULIN SENSIVITY AND METABOLIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 9(5 (41)), 281-287. SID. https://sid.ir/paper/18258/en

Vancouver: Copy

RASTMANESH R., TALEBAN F.A., KIMIAGAR SEYED MASOUD, MEHRABI YAD ELAH. EFFECT OF OMEGA-3 FATTY ACIDS ON INFLAMMATORY MEDIATORS, INSULIN SENSIVITY AND METABOLIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2005;9(5 (41)):281-287. Available from: https://sid.ir/paper/18258/en

IEEE: Copy

R. RASTMANESH, F.A. TALEBAN, SEYED MASOUD KIMIAGAR, and YAD ELAH MEHRABI, “EFFECT OF OMEGA-3 FATTY ACIDS ON INFLAMMATORY MEDIATORS, INSULIN SENSIVITY AND METABOLIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 9, no. 5 (41), pp. 281–287, 2005, [Online]. Available: https://sid.ir/paper/18258/en

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