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Information Journal Paper

Title

THE EFFECT OF OIL EXTRACT OF PORTULACA OLERACEA SEEDS ON INSULIN RESISTANCE INDECES IN MICE

Pages

  313-323

Abstract

DIABETES is the most common endocrine diseases in the world. Recently, the drugs of natural origin especially medicinal plants are considered significant. Purslane (Portulaca oleracea) is an important endemic Iranian vegetable and categorized as an herbal medicine. The aim of this study was to investigate the effect of oil extract of purslane seeds on insulin resistance indeces in MICE. In this study 30 adult MICE were divided into five groups of six: (1) Negative control (non- diabetic), (2) positive control (diabetic), (3) purslane seeds extract control (non-diabetic), (4) 150 (mg/kg) oil extract of purslane seeds (diabetic) and (5) 300 (mg/kg) oil extract of purslane seeds (diabetic). Pursulane exrat gavaged to groups 3, 4 and 5 for one month. After it, DIABETES induction was performed by intra-peritoneal injection of streptozocin in 2nd, 4th and 5th groups. After two month blood samples were taken, indices was measured and analyzed statistically. The overall period of study was 3 months. Oil extract of purslane seeds were decreased significantly serum glucose in diabetic groups in comparison to positive diabetic group (p<0.05). The levels of serum insulin were increased in 3rd, 4th and 5th groups (p<0.05). However, lipid profile, HOMA-IR, QUICKI and atherogenic indeces had not statistically significant changes. Purslan seeds declined serum glucose in diabetic MICE and it had insulinogogic effect.

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    APA: Copy

    KARGARY REZAPOUR, A., & VATANDOUST, R.. (2018). THE EFFECT OF OIL EXTRACT OF PORTULACA OLERACEA SEEDS ON INSULIN RESISTANCE INDECES IN MICE. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 11(4 (44) ), 313-323. SID. https://sid.ir/paper/183017/en

    Vancouver: Copy

    KARGARY REZAPOUR A., VATANDOUST R.. THE EFFECT OF OIL EXTRACT OF PORTULACA OLERACEA SEEDS ON INSULIN RESISTANCE INDECES IN MICE. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2018;11(4 (44) ):313-323. Available from: https://sid.ir/paper/183017/en

    IEEE: Copy

    A. KARGARY REZAPOUR, and R. VATANDOUST, “THE EFFECT OF OIL EXTRACT OF PORTULACA OLERACEA SEEDS ON INSULIN RESISTANCE INDECES IN MICE,” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 11, no. 4 (44) , pp. 313–323, 2018, [Online]. Available: https://sid.ir/paper/183017/en

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