SINGLE VERSUS 7-DAY DOSING OF AMPICILLIN IN THE TREATMENT OF ASYMPTOMATIC BACTERURIA IN PARTURIENTS

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NASOUHI J.; AJORI L.

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Journal: Researcher Bulletin of Medical Sciences Year:2004 | Volume:9 | Issue:1 (37) Page(s): 41-44

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Title

SINGLE VERSUS 7-DAY DOSING OF AMPICILLIN IN THE TREATMENT OF ASYMPTOMATIC BACTERURIA IN PARTURIENTS

Author(s)

NASOUHI J. | AJORI L. | Issue Writer Certificate

Keywords

PREGNANCYQ3

BACTERURIAQ4

AMPICILLINQ4

DOSEQ4

Abstract

Background: According to the popularity of single DOSE antibiotic therapy for asymptomatic BACTERURIA, known complications of long term therapy especially in PREGNANCY and unrecognized effects of single DOSE AMPICILLIN (a common drug in UTI), this study was performed to compare the effect of single versus 7-day dosing of AMPICILLIN on pregnant patients referring to Shohada Tajrish hospital in 2001. Materials and methods: In this clinical trial, 89 pregnant patients who were diagnosed to have asymptomatic BACTERURIA were studied. In the case group (45 patients), 3gr oral AMPICILLIN (6 capsules, 500 mg each) was administered as a single DOSE; the control group (44 patients) received AMPICILLIN, 500 mg every 6 hours for 7 days. Therapeutic effect, resistant and recurrent cases were recorded and the results were analyzed with the appropriate statistical method. Results: Both groups were similar with respect to age, gestational age and gravity. Response to therapy in the single DOSE group was 77.8% and that of the seven day group was 84.1% (p<0.6). Recurrence rate of these groups were 17.8%and 9.1%, respectively (p< 0.3). . Conclusion: It seems as if single DOSE AMPICILLIN is as effective as a 7-day dosing. We recommend using the single DOSE therapy for asymptomatic BACTERURIA in pregnant females.

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APA: Copy

NASOUHI, J., & AJORI, L.. (2004). SINGLE VERSUS 7-DAY DOSING OF AMPICILLIN IN THE TREATMENT OF ASYMPTOMATIC BACTERURIA IN PARTURIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 9(1 (37)), 41-44. SID. https://sid.ir/paper/18633/en

Vancouver: Copy

NASOUHI J., AJORI L.. SINGLE VERSUS 7-DAY DOSING OF AMPICILLIN IN THE TREATMENT OF ASYMPTOMATIC BACTERURIA IN PARTURIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2004;9(1 (37)):41-44. Available from: https://sid.ir/paper/18633/en

IEEE: Copy

J. NASOUHI, and L. AJORI, “SINGLE VERSUS 7-DAY DOSING OF AMPICILLIN IN THE TREATMENT OF ASYMPTOMATIC BACTERURIA IN PARTURIENTS,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 9, no. 1 (37), pp. 41–44, 2004, [Online]. Available: https://sid.ir/paper/18633/en

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