ASSOCIATION BETWEEN GASTRIC DISORDERS AND CAGA OR CAGE IN IRANIAN PATIENTS

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BAGHAEI K.; SHOKRZADEH L.; JAFARI FERESHTEH; BOLFIOUN M.; MASHAYEKHI R.; ZOJAJI H.; ZALI MOHAMMAD REZA

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Journal: Researcher Bulletin of Medical Sciences Year:2010 | Volume:15 | Issue:4 (76) Page(s): 137-142

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Title

ASSOCIATION BETWEEN GASTRIC DISORDERS AND CAGA OR CAGE IN IRANIAN PATIENTS

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Keywords

HELICOBACTER PYLORIQ3

CAGA PROTEINQ3

HELICOBACTER PYLORIQ2

PICB PROTEINQ3

HELICOBACTER PYLORIQ3

CAG EQ3

GASTROINTESTINAL DISEASESQ3

Abstract

Background and Aim: HELICOBACTER PYLORI (H. pylori) is an important pathogen and carcinogen.Generally, pathogenicity of H. pylori is related to cag Patogenicity Island. The famous genes in this region are cagA and cagE. The aim of this study was to evaluate the relation between cagE or cagA and clinical features of Iranian patients.Materials and Methods: The H. pylori was cultured and detected by glmM gene. Polymerase chain reaction was performed to detect cagA and cagE.Results: Among 311 studied patients, 231 were reported as H. pylori positive including 154 (%66.7) patients with cagA and 90 (%39) patients with cagE. There was no significant relation between clinical outcomes (including gastritis, peptic ulcer and gastric cancer) and cagE or cagA.Conclusion: CagA and cagE were not found as suitable markers for diagnosis of gastric disorders.The mentioned result was similar to pervious researches in Iran. In addition, cagA was found to be a better marker compared to cagE.

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APA: Copy

BAGHAEI, K., SHOKRZADEH, L., JAFARI, FERESHTEH, BOLFIOUN, M., MASHAYEKHI, R., ZOJAJI, H., & ZALI, MOHAMMAD REZA. (2010). ASSOCIATION BETWEEN GASTRIC DISORDERS AND CAGA OR CAGE IN IRANIAN PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 15(4 (76)), 137-142. SID. https://sid.ir/paper/18648/en

Vancouver: Copy

BAGHAEI K., SHOKRZADEH L., JAFARI FERESHTEH, BOLFIOUN M., MASHAYEKHI R., ZOJAJI H., ZALI MOHAMMAD REZA. ASSOCIATION BETWEEN GASTRIC DISORDERS AND CAGA OR CAGE IN IRANIAN PATIENTS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2010;15(4 (76)):137-142. Available from: https://sid.ir/paper/18648/en

IEEE: Copy

K. BAGHAEI, L. SHOKRZADEH, FERESHTEH JAFARI, M. BOLFIOUN, R. MASHAYEKHI, H. ZOJAJI, and MOHAMMAD REZA ZALI, “ASSOCIATION BETWEEN GASTRIC DISORDERS AND CAGA OR CAGE IN IRANIAN PATIENTS,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 15, no. 4 (76), pp. 137–142, 2010, [Online]. Available: https://sid.ir/paper/18648/en

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