COMPARISON OF MARGINAL AND MIXED MODELS IN MEDICAL DATA ANALYSIS

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YEKANINEJAD M.S.; YASERI M.; NOURIJELYANI K.; AKABERI A.

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Information Journal Paper

Title

COMPARISON OF MARGINAL AND MIXED MODELS IN MEDICAL DATA ANALYSIS

Author(s)

YEKANINEJAD M.S. | YASERI M. | NOURIJELYANI K. | AKABERI A. | Issue Writer Certificate

Keywords

MARGINAL MODELQ2

MIXED MODELQ2

LINEAR MODELQ2

NON LINEAR MODELQ2

Abstract

Background & Objectives: In medical researchers, there are lots of correlated data which cannot be analyzed using the usual classical statistical methods because the assumption of independency between observations is not met. Data from cluster sampling, longitudinal studies, observations on paired organs and matched studies are examples of such data.Materials & Methods: Two statistical methods that can be used to correctly handle these kinds of data are marginal and MIXED MODELs. These models are different in considering correlation between subjects and Interpretation of the regression coefficients.These models were compared in this paper.Results: The regression coefficients in MARGINAL MODELs with nonidentity link functions show the change in population whereas in MIXED MODELs they represent changes within a subject or a cluster.Conclusion: In result, in nonlinear models, application of these two kinds of models depends on the areas of their usage. While the MARGINAL MODELs are more attractive to the Health policy makers who are considering the potential effects of a variable on the population as a whole, the MIXED MODEL will be of most interest to a physician in a physician/patients context.

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APA: Copy

YEKANINEJAD, M.S., YASERI, M., NOURIJELYANI, K., & AKABERI, A.. (2011). COMPARISON OF MARGINAL AND MIXED MODELS IN MEDICAL DATA ANALYSIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, 3(BIOSTATISTICS AND EPIDEMIOLOGY SUPPLEMENT), 151-159. SID. https://sid.ir/paper/187081/en

Vancouver: Copy

YEKANINEJAD M.S., YASERI M., NOURIJELYANI K., AKABERI A.. COMPARISON OF MARGINAL AND MIXED MODELS IN MEDICAL DATA ANALYSIS. JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;3(BIOSTATISTICS AND EPIDEMIOLOGY SUPPLEMENT):151-159. Available from: https://sid.ir/paper/187081/en

IEEE: Copy

M.S. YEKANINEJAD, M. YASERI, K. NOURIJELYANI, and A. AKABERI, “COMPARISON OF MARGINAL AND MIXED MODELS IN MEDICAL DATA ANALYSIS,” JOURNAL OF NORTH KHORASAN UNIVERSITY OF MEDICAL SCIENCES, vol. 3, no. BIOSTATISTICS AND EPIDEMIOLOGY SUPPLEMENT, pp. 151–159, 2011, [Online]. Available: https://sid.ir/paper/187081/en

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