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Information Journal Paper

Title

NEURONAL DIFFERENTIATION OF EMBRYONAL CARCINOMA STEM CELLS IN THREEDIMENSIONAL CULTURE SYSTEM

Pages

  301-311

Abstract

 Aim: The aim of this study was to use carbon nanotube incorporated electrospun chitosan/polyvinyl alcohol (CS/PVA/CNT) to induce neural differentiation of the stem cells for potential neural tissue engineering applications.Material and Methods: P19 embryonal carcinoma (EC) stem cells were cultured on the CS/PVA/CNT scaffold to induce NEURONAL DIFFERENTIATION. Cresyl violet staining was used to investigate neuronal phenotype and immunoflourescence technique was carried out to evaluate expression of b-tubulin, a neural specific marker.Results: Cresyl violet staining confirmed the neuronal morphology of the differentiated cells. These cells were immunoreactive to neuron specific marker, b-tubulin.Conclusion: the findings suggested the potential use of combined tissue engineering and stem cell therapy to improve deficits in neurodegenerative diseases.

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    APA: Copy

    AZIZI, F., JALIL, H.R., MOSHTAGHIAN, S.J., DOOSTMOHAMMADI, A., & ESMAEILI, F.. (2016). NEURONAL DIFFERENTIATION OF EMBRYONAL CARCINOMA STEM CELLS IN THREEDIMENSIONAL CULTURE SYSTEM. JOURNAL OF CELL & TISSUE, 7(3 ), 301-311. SID. https://sid.ir/paper/188884/en

    Vancouver: Copy

    AZIZI F., JALIL H.R., MOSHTAGHIAN S.J., DOOSTMOHAMMADI A., ESMAEILI F.. NEURONAL DIFFERENTIATION OF EMBRYONAL CARCINOMA STEM CELLS IN THREEDIMENSIONAL CULTURE SYSTEM. JOURNAL OF CELL & TISSUE[Internet]. 2016;7(3 ):301-311. Available from: https://sid.ir/paper/188884/en

    IEEE: Copy

    F. AZIZI, H.R. JALIL, S.J. MOSHTAGHIAN, A. DOOSTMOHAMMADI, and F. ESMAEILI, “NEURONAL DIFFERENTIATION OF EMBRYONAL CARCINOMA STEM CELLS IN THREEDIMENSIONAL CULTURE SYSTEM,” JOURNAL OF CELL & TISSUE, vol. 7, no. 3 , pp. 301–311, 2016, [Online]. Available: https://sid.ir/paper/188884/en

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