OPTIMIZATION OF SUITABLE NITROGEN SOURCES FOR THE PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA

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FIROOZBAKHT MARYAM; AKBARZADEH KOLAHI SAEED; LABEIKI GHAZAL; ATTAR HOSSEIN

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Journal: JOURNAL OF MICROBIAL WORLD Year:2015 | Volume:8 | Issue:3 (24) Page(s): 221-230

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Title

OPTIMIZATION OF SUITABLE NITROGEN SOURCES FOR THE PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA

Author(s)

FIROOZBAKHT MARYAM | AKBARZADEH KOLAHI SAEED | LABEIKI GHAZAL | ATTAR HOSSEIN | Issue Writer Certificate

Keywords

ERYTHROMYCINQ2

SACCHAROPOLYSPORA ERYTHRAEAQ2

WHEY POWDERQ2

Abstract

Background & Objectives: Increase in the yield while reducing costs is one of the most important aspects of researches in biotechnology. Considering the amount of bioproducts consumed annually, antibiotics stand at second place, and therefore there has been considerable research to increase their production. This study was aimed to optimize the media used in fermentation process in terms of nitrogen source.Materials & Methods: This study was conducted in Tehran, based on a continuously sampling from the metabolites produced by SACCHAROPOLYSPORA ERYTHRAEA. After sporulation, seeding and fermentation, the role of WHEY POWDER on several indicators such as pH, biomass production percentage morphological changes in the strain was analyzed. The concentration of the produced ERYTHROMYCIN were examined by spectrophotometry.Results: The results of this study showed the effectiveness of different concentrations of WHEY POWDER on fermentation indices. Also, according to the results, the use of soybean meal with WHEY POWDER had positive impacts on the amount of ERYTHROMYCIN produced, duration of fermentation and the production costs. The optimized concentration of nitrogen nitrogen for production of this antibody was a combination of 54g/l WHEY POWDER with 12g/l soybean meal.Conclusion: Since WHEY POWDER is an inexpensive source of nitrogen, it can be used to reduce costs, and increase the yield. Therefore, WHEY POWDER can be used as an alternative source of nitrogen in industrial production.

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ENHANCEMENT IN PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA BY THE USE OF SUITABLE INDUSTRIAL SEEDING-MEDIA

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APA: Copy

FIROOZBAKHT, MARYAM, AKBARZADEH KOLAHI, SAEED, LABEIKI, GHAZAL, & ATTAR, HOSSEIN. (2015). OPTIMIZATION OF SUITABLE NITROGEN SOURCES FOR THE PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA. JOURNAL OF MICROBIAL WORLD, 8(3 (24)), 221-230. SID. https://sid.ir/paper/189178/en

Vancouver: Copy

FIROOZBAKHT MARYAM, AKBARZADEH KOLAHI SAEED, LABEIKI GHAZAL, ATTAR HOSSEIN. OPTIMIZATION OF SUITABLE NITROGEN SOURCES FOR THE PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA. JOURNAL OF MICROBIAL WORLD[Internet]. 2015;8(3 (24)):221-230. Available from: https://sid.ir/paper/189178/en

IEEE: Copy

MARYAM FIROOZBAKHT, SAEED AKBARZADEH KOLAHI, GHAZAL LABEIKI, and HOSSEIN ATTAR, “OPTIMIZATION OF SUITABLE NITROGEN SOURCES FOR THE PRODUCTION OF ERYTHROMYCIN BY SACCHAROPOLYSPORA ERYTHRAEA,” JOURNAL OF MICROBIAL WORLD, vol. 8, no. 3 (24), pp. 221–230, 2015, [Online]. Available: https://sid.ir/paper/189178/en

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