EFFECT OF HYDRO-ETHANOLIC EXTRACT OF CURRANT ON AMOUNT OF ANXIETY IN ADULT MALE MICE IN PLUS MAZE MODEL

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HOSSEINI SEYYED EBRAHIM; AVAZPOUR YASAMAN

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Journal: JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES) Year:2016 | Volume:9 | Issue:2 (33) Page(s): 57-62

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Title

EFFECT OF HYDRO-ETHANOLIC EXTRACT OF CURRANT ON AMOUNT OF ANXIETY IN ADULT MALE MICE IN PLUS MAZE MODEL

Author(s)

HOSSEINI SEYYED EBRAHIM | AVAZPOUR YASAMAN | Issue Writer Certificate

Keywords

CURRANTQ1

ANXIETYQ2

ELEVATED PLUS MAZEQ1

MICEQ2

Abstract

Inroduction & Objective: ANXIETY is one of the most widespread psychological disorders which may lead to functional disorders, chronic diseases and decrease in life style. Considering the side effects caused by chemical drugs, this study was carried out to investigate the effect of hydro-ethanolic extract of CURRANT on amount of stress in adult male MICE with the goal of finding a safer way for managing stress.Material and Methods: In this experimental study 40 adult male MICE were used falling into 5 groups including: Control (no treatment), Sham (consuming distilled water), and 3 experimental groups (gavaged with three concentrations of hydro-ethanolic extract of CURRANT (200, 100, 400 mg/kg). The level ANXIETY was measured by ELEVATED PLUS MAZE. The duration and number of presence of each mouse in closed and open arms were determined. The results were analyzed using ANOVA test with Tukey post hoc.Results: Results showed that hydro-ethanolic extract of CURRANT at doses of 100, 200 and 400 mg/kg BW caused a significant reduction in ANXIETY.Conclusions: According to the findings, it appears that the extract of CURRANT with flavonoids compounds as GABA receptor agonists and increase serotonin may reduce ANXIETY in ELEVATED PLUS MAZE.

Cites

STUDY OF THE ANXIOLYTIC EFFECTS OF PLANTGO MAJOR L. AND POSSIBLE ROLE OF GABAERGIC SYSTEM IN THESE EFFECTS IN RATS

References

مقایسه اثر عصاره هیدروالکلی مویز و دیازپام بر میزان سرمی هورمون کورتیکوسترون در موش های سفید آزمایشگاهی نر بالغ

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APA: Copy

HOSSEINI, SEYYED EBRAHIM, & AVAZPOUR, YASAMAN. (2016). EFFECT OF HYDRO-ETHANOLIC EXTRACT OF CURRANT ON AMOUNT OF ANXIETY IN ADULT MALE MICE IN PLUS MAZE MODEL. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), 9(2 (33)), 57-62. SID. https://sid.ir/paper/191807/en

Vancouver: Copy

HOSSEINI SEYYED EBRAHIM, AVAZPOUR YASAMAN. EFFECT OF HYDRO-ETHANOLIC EXTRACT OF CURRANT ON AMOUNT OF ANXIETY IN ADULT MALE MICE IN PLUS MAZE MODEL. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES)[Internet]. 2016;9(2 (33)):57-62. Available from: https://sid.ir/paper/191807/en

IEEE: Copy

SEYYED EBRAHIM HOSSEINI, and YASAMAN AVAZPOUR, “EFFECT OF HYDRO-ETHANOLIC EXTRACT OF CURRANT ON AMOUNT OF ANXIETY IN ADULT MALE MICE IN PLUS MAZE MODEL,” JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), vol. 9, no. 2 (33), pp. 57–62, 2016, [Online]. Available: https://sid.ir/paper/191807/en

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