EFFECT OF RANITIDINE ON PREVENTION OF PENTAGASTRIN STIMULATED ABOMASAL FUNDIC SECRETION IN SHEEP

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MOSTAGHNI K.; BADIEI K.; KOJOURI G.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Year:2001 | Volume:14 | Issue:2 (51 IN ANIMAL SCIENCES) Page(s): 100-101

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Title

EFFECT OF RANITIDINE ON PREVENTION OF PENTAGASTRIN STIMULATED ABOMASAL FUNDIC SECRETION IN SHEEP

Author(s)

MOSTAGHNI K. | BADIEI K. | KOJOURI G. | Issue Writer Certificate

Keywords

RANITIDINEQ4

PENTAGASTRINQ4

ABOMASUMQ4

SHEEPQ3

Abstract

The efficacy of RANITIDINE for inhibition of stimulated gastric secretion was evaluated in ten healthy SHEEP. An abomasal fundic pouch was made under thiopental sodium anaesthesia described by Mostaghni and Howard in each animal. Hay and water was provided ad lib.Control gastric juice samples were collected following administration of distilled water (2ml, 1M) at different times (0.5, 1, 1.5, 2 and 2.5 hours).RANITIDINE (1.5 and 3 mg/kg.1M) was administered at time zero and 30 minutes after PENTAGASTRIN (4, ug/kg, SC) was adsministered. Gastric juice samples were obtained every 30 minutes for 2.5 hours following the first injection. It was shown that RANITIDINE effectively reduces volume. total acidity, K and chloride concentrations and increases pH and Na concentration of gastric juice 30 minutes before PENTAGASTRIN stimulated secretion in clinically normal fed SHEEP (p<0.05).Furthermore there were no significant changes in pepsin concentration (mg Tyrosine/24h.) during the experiment (p>0.05).

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APA: Copy

MOSTAGHNI, K., BADIEI, K., & KOJOURI, G.. (2001). EFFECT OF RANITIDINE ON PREVENTION OF PENTAGASTRIN STIMULATED ABOMASAL FUNDIC SECRETION IN SHEEP. PAJOUHESH-VA-SAZANDEGI, 14(2 (51 IN ANIMAL SCIENCES)), 100-101. SID. https://sid.ir/paper/19411/en

Vancouver: Copy

MOSTAGHNI K., BADIEI K., KOJOURI G.. EFFECT OF RANITIDINE ON PREVENTION OF PENTAGASTRIN STIMULATED ABOMASAL FUNDIC SECRETION IN SHEEP. PAJOUHESH-VA-SAZANDEGI[Internet]. 2001;14(2 (51 IN ANIMAL SCIENCES)):100-101. Available from: https://sid.ir/paper/19411/en

IEEE: Copy

K. MOSTAGHNI, K. BADIEI, and G. KOJOURI, “EFFECT OF RANITIDINE ON PREVENTION OF PENTAGASTRIN STIMULATED ABOMASAL FUNDIC SECRETION IN SHEEP,” PAJOUHESH-VA-SAZANDEGI, vol. 14, no. 2 (51 IN ANIMAL SCIENCES), pp. 100–101, 2001, [Online]. Available: https://sid.ir/paper/19411/en

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