THE STUDY AND COMPARISON OF THE QUANTITY OF AMINO ACIDS IN THE SKIN OF DOGS DIAGNOSED WITH DERMATOPHYTOSIS AND IN HEALTHY DOGS

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JAFARI ARYAN N.; HASHEMI S.J.; MASHHADI RAFIEE S.; FIROOZRAI M.

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Paper Information

Journal: JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN Year:2014 | Volume:11 (NEW) | Issue:2 (45) Page(s): 1267-1273

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Title

THE STUDY AND COMPARISON OF THE QUANTITY OF AMINO ACIDS IN THE SKIN OF DOGS DIAGNOSED WITH DERMATOPHYTOSIS AND IN HEALTHY DOGS

Author(s)

JAFARI ARYAN N. | HASHEMI S.J. | MASHHADI RAFIEE S. | FIROOZRAI M. | Issue Writer Certificate

Keywords

STRATUM CORNEUMQ2

DERMATOPHYTOSISQ3

AMINO ACIDSQ2

DOGSQ2

Abstract

The STRATUM CORNEUM includes keratinocyte cells; this is the first defense layer which stands in the face of pathogenic microorganisms. Identifying the components of STRATUM CORNEUM can provide plenty of information on its resistance against superficial infections. STRATUM CORNEUM contains higher amount of AMINO ACIDS which most of them can serve as a source of nitrogen for the growth and colonization of dermathophytes. The objective behind this study is to investigate and compare the quantity of AMINO ACIDS in DOGS diagnosed with dermathophytosis and in healthy DOGS.30 DOGS suspected lesions of DERMATOPHYTOSIS and 30 healthy DOGS were used in this study. Skin scraping samples from 30 DOGS with no obvious skin lesions and from 30 DOGS suspected lesions of DERMATOPHYTOSIS were taken. AMINO ACIDS were analyzed by highperformance liquid chromatography in both groups. Between two groups, significant differences were found for the rate of aspartic acids, serine and asparagine AMINO ACIDS. Aspartic acid seems to play inhibitory role in growth and colonization of dermathophytes in a way that less of it is found in infected DOGS compared with healthy counterparts. It seems asparagine and serine has a stimulatory role in the growth and colonization of dermathophytes. The inhibitory properties of aspartic acids are suggested to be used in the manufacture of more effective antifungal agents especially for chronic type of DERMATOPHYTOSIS.

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APA: Copy

JAFARI ARYAN, N., HASHEMI, S.J., MASHHADI RAFIEE, S., & FIROOZRAI, M.. (2014). THE STUDY AND COMPARISON OF THE QUANTITY OF AMINO ACIDS IN THE SKIN OF DOGS DIAGNOSED WITH DERMATOPHYTOSIS AND IN HEALTHY DOGS. JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN, 11 (NEW)(2 (45)), 1267-1273. SID. https://sid.ir/paper/197427/en

Vancouver: Copy

JAFARI ARYAN N., HASHEMI S.J., MASHHADI RAFIEE S., FIROOZRAI M.. THE STUDY AND COMPARISON OF THE QUANTITY OF AMINO ACIDS IN THE SKIN OF DOGS DIAGNOSED WITH DERMATOPHYTOSIS AND IN HEALTHY DOGS. JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN[Internet]. 2014;11 (NEW)(2 (45)):1267-1273. Available from: https://sid.ir/paper/197427/en

IEEE: Copy

N. JAFARI ARYAN, S.J. HASHEMI, S. MASHHADI RAFIEE, and M. FIROOZRAI, “THE STUDY AND COMPARISON OF THE QUANTITY OF AMINO ACIDS IN THE SKIN OF DOGS DIAGNOSED WITH DERMATOPHYTOSIS AND IN HEALTHY DOGS,” JOURNAL OF COMPARATIVE PATHOBIOLOGY IRAN, vol. 11 (NEW), no. 2 (45), pp. 1267–1273, 2014, [Online]. Available: https://sid.ir/paper/197427/en

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