Identification of gene expression biomarkers to detect illicit use of steroid growth stimulators in slaughterhouses

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ROUDBARI Z.; Sattaei Mokhtari m.; BARAZANDEH A.; SEYEDABADI H.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Veterinary Research & Biological Products Year:2019 | Volume:32 | Issue:3 (124) Page(s): 2-8

Download Full-Text

Persian Verion

View:

526

Download:

Cites:

Information Journal Paper

Title

Identification of gene expression biomarkers to detect illicit use of steroid growth stimulators in slaughterhouses

Author(s)

ROUDBARI Z. | Sattaei Mokhtari m. | BARAZANDEH A. | SEYEDABADI H.R. | Issue Writer Certificate

Keywords

Candidate biomarkerQ1

Fraud detectionQ1

Biology pathwayQ1

gene expression analysisQ1

Abstract

Consideration of the residual growth hormones in the carcass of slaughtered animals in the slaughterhouse is necessary as a potential risk to the health of the community. The present study aimed at identifying biomarkers to detect the illegal use of growth stimulating hormones in slaughter houses. For this purpose, the differential expression analysis of the genes in a gene expression profile in the Arrayexpress database with the accession number E-GEOD-12179 was initially comprised of a comparison of the muscle tissue of the beef cattle receiving the growth stimulating hormone with beef cattle muscle, which did not receive any growth stimulating hormones. Among genes with different expression, target genes were identified by analyzing the statistical parameters of the network. The identified genes were MAPK1, EDN1, TGFB1, BMP4, and PPARA. Then the pathway analysis of the gene, generating and analyzing the expression network of genes based on target genes were performed using Pathvisio, Cytoscape and Pathway studio software. Analysis of pathways showed that beta-cell growth factor, growth factor receptor, and gonadotropin hormone release were significant. Also, the results of this analysis showed that these genes play a role in the regulation of cellular cell proliferation, differentiation, development, and process of muscle hypertrophy. Therefore, these genes have the potential for introduction as biomarkers of gene expression in relation to the detection of the use of growth promoters and provide new markers for detecting illegal use of growth stimulating hormones in slaughterhouses.

Cites

No record.

References

No record.

Cite

APA: Copy

ROUDBARI, Z., Sattaei Mokhtari, m., BARAZANDEH, A., & SEYEDABADI, H.R.. (2019). Identification of gene expression biomarkers to detect illicit use of steroid growth stimulators in slaughterhouses. VETERINARY RESEARCHES BIOLOGICAL PRODUCTS (PAJOUHESH-VA-SAZANDEGI), 32(3 (124) ), 2-8. SID. https://sid.ir/paper/200909/en

Vancouver: Copy

ROUDBARI Z., Sattaei Mokhtari m., BARAZANDEH A., SEYEDABADI H.R.. Identification of gene expression biomarkers to detect illicit use of steroid growth stimulators in slaughterhouses. VETERINARY RESEARCHES BIOLOGICAL PRODUCTS (PAJOUHESH-VA-SAZANDEGI)[Internet]. 2019;32(3 (124) ):2-8. Available from: https://sid.ir/paper/200909/en

IEEE: Copy

Z. ROUDBARI, m. Sattaei Mokhtari, A. BARAZANDEH, and H.R. SEYEDABADI, “Identification of gene expression biomarkers to detect illicit use of steroid growth stimulators in slaughterhouses,” VETERINARY RESEARCHES BIOLOGICAL PRODUCTS (PAJOUHESH-VA-SAZANDEGI), vol. 32, no. 3 (124) , pp. 2–8, 2019, [Online]. Available: https://sid.ir/paper/200909/en

Related Journal Papers