Chromatin Replication and Epigenome Maintenance

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DEHGHANIAN FARIBA; MOTOVALI BASHI MAJID; Akbari Atefe

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Journal Paper

Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2019 | Volume:9 | Issue:35 Page(s): 9-23

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Information Journal Paper

Title

Chromatin Replication and Epigenome Maintenance

Author(s)

DEHGHANIAN FARIBA | MOTOVALI BASHI MAJID | Akbari Atefe | Issue Writer Certificate

Keywords

nucleosomeQ2

nucleosome assembly and disassemblyQ1

chromatin proteinsQ1

replication forkQ1

Abstract

The eukaryotic replisome is a multi-component complex that drives DNA replication with a speed of approximately 2 to 3 kb per min. This implies that chromatin is disrupted at a rate of around 10 to 15 nucleosomes every minute a head of each active replisome. To reproduce a similar chromatin environment on new DNA, histones and other chromatin-bound factors are transferred from the parental strand to the daughter strands. In addition, new histones are incorporated to maintain nucleosome density, and their modification signature should be assimilated to nearby old histones in the local chromatin environment. In general interaction between the components of the replisome and chromatin proteins can help to understand the proper way of improving the replication fork and its relationship to chromatin. In this study, the regulatory mechanism of chromatin replication and epigenome maintenance are evaluated.

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APA: Copy

DEHGHANIAN, FARIBA, MOTOVALI BASHI, MAJID, & Akbari, Atefe. (2019). Chromatin Replication and Epigenome Maintenance. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 9(35 ), 9-23. SID. https://sid.ir/paper/204512/en

Vancouver: Copy

DEHGHANIAN FARIBA, MOTOVALI BASHI MAJID, Akbari Atefe. Chromatin Replication and Epigenome Maintenance. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2019;9(35 ):9-23. Available from: https://sid.ir/paper/204512/en

IEEE: Copy

FARIBA DEHGHANIAN, MAJID MOTOVALI BASHI, and Atefe Akbari, “Chromatin Replication and Epigenome Maintenance,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 9, no. 35 , pp. 9–23, 2019, [Online]. Available: https://sid.ir/paper/204512/en

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