مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

1,088
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

INVESTIGATION OF INNATE IMMUNE SIGNALING CONCERNED WITH SIRNA FROM A MOLECULAR VIEWPOINT

Pages

  9-15

Abstract

 RNA interference (RNAI) has emerged as a powerful tool to suppress gene expression in a variety of cell lines by mediated small interfering RNAs (siRNA). In addition to the gene-silencing activity of SIRNA, it can induce pro-inflammatory cytokines and type I interferon. RNA-sensing immonoreceptors include Toll-like receptor (TLR) family and cytosolic RNA-sensing proteins like Protein Kinase R (PKR), 2’-5’ Oligo adenylate synthetase (2’-5’OAS), Retinoic-acid Inducible Gene -I (RIG-I), Melanoma Differentiation-associated gene-5 (MDA-5) and Nuclear Factor kappa B cell (NF-kB). Induction of IFN can be raised the signaling pathways associated with the TLR. Each of receptors group is able to induce signals in response to a variety of ligands, initiating the pro inflammatory cytokines response. This review article describes gene silencing, the role of cellular factors in INNATE IMMUNITY GENE REGULATION and induction of interferon by double-stranded and single stranded SIRNA.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    MOHAJERI, N., & KAZEMI, B.. (2012). INVESTIGATION OF INNATE IMMUNE SIGNALING CONCERNED WITH SIRNA FROM A MOLECULAR VIEWPOINT. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 2(6), 9-15. SID. https://sid.ir/paper/204669/en

    Vancouver: Copy

    MOHAJERI N., KAZEMI B.. INVESTIGATION OF INNATE IMMUNE SIGNALING CONCERNED WITH SIRNA FROM A MOLECULAR VIEWPOINT. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2012;2(6):9-15. Available from: https://sid.ir/paper/204669/en

    IEEE: Copy

    N. MOHAJERI, and B. KAZEMI, “INVESTIGATION OF INNATE IMMUNE SIGNALING CONCERNED WITH SIRNA FROM A MOLECULAR VIEWPOINT,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 2, no. 6, pp. 9–15, 2012, [Online]. Available: https://sid.ir/paper/204669/en

    Related Journal Papers

    Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops





    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button