ASSESSMENT OF THE EFFECTS OF ANTI-INFLAMMATORY OF GARLIC; NETTLE LEAVES AND OLIVES EXTRACTS IN STZ-INDUCED DIABETIC RAT

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DARABI S.; HASANVAND A.; NOUROLLAHI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Complementary Medicine Journal Year:2016 | Volume:6 | Issue:1 (18) Page(s): 1452-1460

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Title

ASSESSMENT OF THE EFFECTS OF ANTI-INFLAMMATORY OF GARLIC; NETTLE LEAVES AND OLIVES EXTRACTS IN STZ-INDUCED DIABETIC RAT

Author(s)

DARABI S. | HASANVAND A. | NOUROLLAHI A. | Issue Writer Certificate

Keywords

GARLIC EXTRACTQ3

NETTLE LEAVES EXTRACTQ3

OLIVE EXTRACT INFLAMMATION CYTOKINESQ3

DIABETESQ3

Abstract

Introduction: It has been demonstrated that the inflammatory markers such as IL-6, TNF-a and CRP are increased in STZ-diabetic rats. The present study is to investigate the effects of medicinal plants used in traditional medicine, including GARLIC EXTRACT; NETTLE LEAVES EXTRACT and olive extract on serum hsCRP and IL-6 and TNF-a on the rats with DIABETES.Methods: DIABETES was induced in male wistar rats by single injection streptozotocin (60 mg/kg). GARLIC EXTRACT, NETTLE LEAVES EXTRACT and olive extract were used one day after induction of DIABETES until three weeks after STZ-diabetes induction. In this study the animals were divided into five groups: control, diabetic, diabetic + GARLIC EXTRACT (50 mg / kg), DIABETES + Nettle leaf extract (30 mg / kg), and DIABETES + Olive extract (30 mg / kg). After 21 days, serum levels of inflammatory factors were measured using ELISA kits.Results: The results showed that the serum levels of hsCRP and IL-6 and TNF-a in the target groups, the use of medicinal plants extracts, as compared to untreated diabetics have significantly decreased.Conclusion: The results showed that administration of GARLIC EXTRACT, nettle extract and olive extract significantly attenuated levels inflammatory markers such as IL-6, TNF-a and CRP in diabetic rats.

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APA: Copy

DARABI, S., HASANVAND, A., & NOUROLLAHI, A.. (2016). ASSESSMENT OF THE EFFECTS OF ANTI-INFLAMMATORY OF GARLIC; NETTLE LEAVES AND OLIVES EXTRACTS IN STZ-INDUCED DIABETIC RAT. COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY, 6(1 (18)), 1452-1460. SID. https://sid.ir/paper/215364/en

Vancouver: Copy

DARABI S., HASANVAND A., NOUROLLAHI A.. ASSESSMENT OF THE EFFECTS OF ANTI-INFLAMMATORY OF GARLIC; NETTLE LEAVES AND OLIVES EXTRACTS IN STZ-INDUCED DIABETIC RAT. COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY[Internet]. 2016;6(1 (18)):1452-1460. Available from: https://sid.ir/paper/215364/en

IEEE: Copy

S. DARABI, A. HASANVAND, and A. NOUROLLAHI, “ASSESSMENT OF THE EFFECTS OF ANTI-INFLAMMATORY OF GARLIC; NETTLE LEAVES AND OLIVES EXTRACTS IN STZ-INDUCED DIABETIC RAT,” COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY, vol. 6, no. 1 (18), pp. 1452–1460, 2016, [Online]. Available: https://sid.ir/paper/215364/en

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