DOES ADDING KETAMIN OR NEOSTIGMINE TO BUPIVACAINE IMPROVE CAUDAL ANALGESIA IN PEDIATRIC PATIENTS?

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ARBABI SHAHRIAR; SHIRMOHAMMADI MOOSA; EBRAHIM SOLTANI ALIREZA; ZIAEEFARD MOHSEN; JALALI FARAHANI ALIREZA; GOUDARZI MEHRDAD; NAJMI EHSANOLLAH

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Journal: Journal of Anesthesiology and Pain Year:2013 | Volume:3 | Issue:3 Page(s): 155-160

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Title

DOES ADDING KETAMIN OR NEOSTIGMINE TO BUPIVACAINE IMPROVE CAUDAL ANALGESIA IN PEDIATRIC PATIENTS?

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Keywords

CAUDAL ANALGESIAQ3

BUPIVACAINEQ3

S-KETAMINEQ3

NEOSTIGMINEQ2

Abstract

Aim and Background: This clinical trial was conducted to evaluate the effectiveness of adding NEOSTIGMINE or S-Ketmine to caudal BUPIVACAINE to prolong analgesia.Methods and Materials: 60 pediatric patients scheduled for elective surgery below umbilicus with ASA physical status I or II were enrolled in this double blinded clinical trial. The patients were placed in three different groups based on local anesthetic solution prepared for caudal anesthesia. In the 1st group 1 ml/kg of 0.25% BUPIVACAINE, in the 2nd group 1 ml/kg of 0.25% BUPIVACAINE plus 0.5 mg ketamine and finally in the 3rd group 1 ml/kg of 0.25% BUPIVACAINE with 2 mg/kg NEOSTIGMINE were used. Postoperative pain was evaluated using Face pain scale in the postoperative recovery unit.Findings: The mean duration of postoperative analgesia was 23 h in NEOSTIGMINE group, 14.5 h in keamine group, and 8 h in control patients. Although there were more episodes of nausea and vomiting plus emergence reaction in group 2, no statistical significant difference was observed. Conclusions: Addition of preservative-free S-KETAMINE (0.5 mg/kg) or 2mg/kg NEOSTIGMINE, to caudal BUPIVACAINE provides significant prolongation of analgesia without producing profound negative side-effects.

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APA: Copy

ARBABI, SHAHRIAR, SHIRMOHAMMADI, MOOSA, EBRAHIM SOLTANI, ALIREZA, ZIAEEFARD, MOHSEN, JALALI FARAHANI, ALIREZA, GOUDARZI, MEHRDAD, & NAJMI, EHSANOLLAH. (2013). DOES ADDING KETAMIN OR NEOSTIGMINE TO BUPIVACAINE IMPROVE CAUDAL ANALGESIA IN PEDIATRIC PATIENTS?. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 3(3), 155-160. SID. https://sid.ir/paper/216350/en

Vancouver: Copy

ARBABI SHAHRIAR, SHIRMOHAMMADI MOOSA, EBRAHIM SOLTANI ALIREZA, ZIAEEFARD MOHSEN, JALALI FARAHANI ALIREZA, GOUDARZI MEHRDAD, NAJMI EHSANOLLAH. DOES ADDING KETAMIN OR NEOSTIGMINE TO BUPIVACAINE IMPROVE CAUDAL ANALGESIA IN PEDIATRIC PATIENTS?. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2013;3(3):155-160. Available from: https://sid.ir/paper/216350/en

IEEE: Copy

SHAHRIAR ARBABI, MOOSA SHIRMOHAMMADI, ALIREZA EBRAHIM SOLTANI, MOHSEN ZIAEEFARD, ALIREZA JALALI FARAHANI, MEHRDAD GOUDARZI, and EHSANOLLAH NAJMI, “DOES ADDING KETAMIN OR NEOSTIGMINE TO BUPIVACAINE IMPROVE CAUDAL ANALGESIA IN PEDIATRIC PATIENTS?,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 3, no. 3, pp. 155–160, 2013, [Online]. Available: https://sid.ir/paper/216350/en

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