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Title

COMPARATIVE ANTIMICROBIAL EFFECT OF A DRUG COMBINATION (CIPROJLOXACIN, METRONIDAZOLE AND TETRACYCLINE) AND CALCIUM HYDROXIDE ON INFECTED ROOT DENTINAL TUBULES - IN VITRO

Pages

  257-284

Abstract

 Bacteria and their products play a major role in initiation and perpetuation of pulpo-periapical pathosis, and therefore the most important phase of endodontic treatment is the elimination or reduction of bacteria from root canal system.The purpose of this study was to compare the ANTIMICROBIAL effects of two intracanal agents, an antibiotic combination and CALCIUM HYDROXIDE on infected dentinal tubules.Dentinal tubules of 60 root canal specimens of human teeth were infected with Enterococcus faecalis (RITCC 1918) for 3 weeks, and then exposed to a CALCIUM HYDROXIDE / saline paste or a mixure of CIPROFLOXACIN, METRONIDAZOLe and TETRACYCLINE (25 microgram/ml of each drug) for periods of 24h, 48h, 7days.The bacteriological samples were taken by shaving the inner dentine from root canal with dental bur. Powder samples were incubated and the quantity of bacteria present assessed using spectrophotometry. Furthermore, the target organisms were cultured on blood agar plates and total numbers of colony forming units/m1 (CPU/m1) were counted.Results indicated that the drug combination effectively kills bacteria in the tubules after a 24h period of exposure, in contrast CALCIUM HYDROXIDE was in effective against E.faecalis even after 1 week of exposure.

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    APA: Copy

    KANGARLOU, A., MEHR VARZFAR, P., GHAZI SAEIDI, KIOUMARS, & ASNA ASHARI, M.. (2000). COMPARATIVE ANTIMICROBIAL EFFECT OF A DRUG COMBINATION (CIPROJLOXACIN, METRONIDAZOLE AND TETRACYCLINE) AND CALCIUM HYDROXIDE ON INFECTED ROOT DENTINAL TUBULES - IN VITRO . JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 18(3), 257-284. SID. https://sid.ir/paper/21745/en

    Vancouver: Copy

    KANGARLOU A., MEHR VARZFAR P., GHAZI SAEIDI KIOUMARS, ASNA ASHARI M.. COMPARATIVE ANTIMICROBIAL EFFECT OF A DRUG COMBINATION (CIPROJLOXACIN, METRONIDAZOLE AND TETRACYCLINE) AND CALCIUM HYDROXIDE ON INFECTED ROOT DENTINAL TUBULES - IN VITRO . JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2000;18(3):257-284. Available from: https://sid.ir/paper/21745/en

    IEEE: Copy

    A. KANGARLOU, P. MEHR VARZFAR, KIOUMARS GHAZI SAEIDI, and M. ASNA ASHARI, “COMPARATIVE ANTIMICROBIAL EFFECT OF A DRUG COMBINATION (CIPROJLOXACIN, METRONIDAZOLE AND TETRACYCLINE) AND CALCIUM HYDROXIDE ON INFECTED ROOT DENTINAL TUBULES - IN VITRO ,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 18, no. 3, pp. 257–284, 2000, [Online]. Available: https://sid.ir/paper/21745/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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