INVITRO EVALUATION OF CYTOTOXICITY AND ELEMENTAL RELEASE OF THREE TYPES OF NICKEL-CHROMIUM BASEMETAL ALLOYS AND COMPARISON WITH ONE TYPE OF HIGH NOBLE (GOLD-PALLADIUM-SILVER) ALLOY

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ROKNI SH.; JAFARI MAHMOUD REZA; KOUSHA SARA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Dental School Year:2007 | Volume:25 | Issue:3 (73) Page(s): 261-268

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Title

INVITRO EVALUATION OF CYTOTOXICITY AND ELEMENTAL RELEASE OF THREE TYPES OF NICKEL-CHROMIUM BASEMETAL ALLOYS AND COMPARISON WITH ONE TYPE OF HIGH NOBLE (GOLD-PALLADIUM-SILVER) ALLOY

Author(s)

ROKNI SH. | JAFARI MAHMOUD REZA | KOUSHA SARA | Issue Writer Certificate

Keywords

BASE METAL ALLOYQ3

ELEMENTAL RELEASEQ3

BIOCOMPATIBILITYQ3

CYTOTOXICITYQ3

Abstract

Background & Aim: Dental alloys following corrosion cause changes in oral tissues. As BASE METAL ALLOYs are used for fabrication of dental prostheses and are manufactured in Iran, the aim of this study was to investigate the CYTOTOXICITY of three types of nickel - chromium BASE METAL ALLOYs with one type of high noble alloy on mouse fibroblast cell (L 929) by MTT test.Methods & Materials: In this experimental study, 12 disks of each alloy with 5mm diameter and 2.5 mm thickness were prepared and placed in RPMI culture medium for 48 hours & 72 hours (extract medium). Then the extract mediums were diluted in two different dilutions of 200 ml & 40 ml and their CYTOTOXICITY were evaluated by MTT assay and compared with two control groups consist of only culture media & culture media with teflon. The amount of Nickel, chromium, copper, zinc & silver released from each alloys were measured by flame atomic absorption device.The data were analyzed by Graph Instate software, one way ANOV A and Tukey tests.Result: After 48 hours, no significant difference in CYTOTOXICITY was found between samples and control groups. After 72 hours there was a significant difference between samples and control groups (Minalux vs. Control: P<0.01, Degubond vs. Control: P<0.001, Wiron 99 vs. Control: P<0.001, Supercast vs. Control: P<0.05). There was no significant difference in CYTOTOXICITY with two dilutions of 200 ml & 40 ml between samples. Maximum release of nickel and chromium were observed from Minalux, silver from Degubond and zinc from Supercast.Conclusion: The CYTOTOXICITY of three Nickel-Chromium alloys and one high noble which were used in this study was "pot different. CYTOTOXICITY increased with time.

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APA: Copy

ROKNI, SH., JAFARI, MAHMOUD REZA, & KOUSHA, SARA. (2007). INVITRO EVALUATION OF CYTOTOXICITY AND ELEMENTAL RELEASE OF THREE TYPES OF NICKEL-CHROMIUM BASEMETAL ALLOYS AND COMPARISON WITH ONE TYPE OF HIGH NOBLE (GOLD-PALLADIUM-SILVER) ALLOY. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 25(3 (73)), 261-268. SID. https://sid.ir/paper/21877/en

Vancouver: Copy

ROKNI SH., JAFARI MAHMOUD REZA, KOUSHA SARA. INVITRO EVALUATION OF CYTOTOXICITY AND ELEMENTAL RELEASE OF THREE TYPES OF NICKEL-CHROMIUM BASEMETAL ALLOYS AND COMPARISON WITH ONE TYPE OF HIGH NOBLE (GOLD-PALLADIUM-SILVER) ALLOY. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2007;25(3 (73)):261-268. Available from: https://sid.ir/paper/21877/en

IEEE: Copy

SH. ROKNI, MAHMOUD REZA JAFARI, and SARA KOUSHA, “INVITRO EVALUATION OF CYTOTOXICITY AND ELEMENTAL RELEASE OF THREE TYPES OF NICKEL-CHROMIUM BASEMETAL ALLOYS AND COMPARISON WITH ONE TYPE OF HIGH NOBLE (GOLD-PALLADIUM-SILVER) ALLOY,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 25, no. 3 (73), pp. 261–268, 2007, [Online]. Available: https://sid.ir/paper/21877/en

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