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Information Journal Paper

Title

THE EFFECT OF AEROBIC EXERCISE ON LIPID PEROXIDATION AND ANTIOXIDANT ENZYMES ACTIVITY IN HIPPOCAMPUS FOLLOWING CEREBRAL ISCHEMIA - REPERFUSION IN MALE RATS

Pages

  33-41

Abstract

 Cerebral ISCHEMIA is associated with extensive metabolic disorders in the nerve cells especially the hippocampal neurons. Evidence suggests that EXERCISE has neuroprotective effects and can protect the brain from ischemic injury. This study aimed at investigating the effect of pre-ischemic EXERCISE on LIPID PEROXIDATION and ANTIOXIDANT ENZYMES activity in HIPPOCAMPUS.21 male Wistar rats were randomly divided into three groups: sham, EXERCISE+ischemia and ISCHEMIA. The rats in EXERCISE group were trained to run on a treadmill 5 days a week for 4 weeks. Brain ISCHEMIA was induced by an occlusion of common carotid arteries for 20 minutes. Malondialdehyde (MDA) and ANTIOXIDANT ENZYMES activity (SOD, GPX, and CAT) were measured using special kits. The results showed that EXERCISE significantly decreased MDA concentration and significantly increased ANTIOXIDANT ENZYMES activity in the HIPPOCAMPUS. Generally, EXERCISE can have protective effects against brain ISCHEMIA-induced injuries and disorders by an increase in the ANTIOXIDANT ENZYMES activity.

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    APA: Copy

    Shamsaei, Nabi, Abdi, Hadi, & FARZAD, BABAK. (2017). THE EFFECT OF AEROBIC EXERCISE ON LIPID PEROXIDATION AND ANTIOXIDANT ENZYMES ACTIVITY IN HIPPOCAMPUS FOLLOWING CEREBRAL ISCHEMIA - REPERFUSION IN MALE RATS. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, 9(3 ), 33-41. SID. https://sid.ir/paper/222209/en

    Vancouver: Copy

    Shamsaei Nabi, Abdi Hadi, FARZAD BABAK. THE EFFECT OF AEROBIC EXERCISE ON LIPID PEROXIDATION AND ANTIOXIDANT ENZYMES ACTIVITY IN HIPPOCAMPUS FOLLOWING CEREBRAL ISCHEMIA - REPERFUSION IN MALE RATS. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS[Internet]. 2017;9(3 ):33-41. Available from: https://sid.ir/paper/222209/en

    IEEE: Copy

    Nabi Shamsaei, Hadi Abdi, and BABAK FARZAD, “THE EFFECT OF AEROBIC EXERCISE ON LIPID PEROXIDATION AND ANTIOXIDANT ENZYMES ACTIVITY IN HIPPOCAMPUS FOLLOWING CEREBRAL ISCHEMIA - REPERFUSION IN MALE RATS,” SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, vol. 9, no. 3 , pp. 33–41, 2017, [Online]. Available: https://sid.ir/paper/222209/en

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