THE EFFECT OF PGE2 AND CALCIUM GLUCONATE ON ROOT RESORPTION IN RATS

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SEYFI M.; ESLAMI B.

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Journal: Journal of Dental School Year:2002 | Volume:20 | Issue:3 Page(s): 316-321

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Title

THE EFFECT OF PGE2 AND CALCIUM GLUCONATE ON ROOT RESORPTION IN RATS

Author(s)

SEYFI M. | ESLAMI B. | Issue Writer Certificate

Keywords

ROOT RESORPTIONQ3

CALCIUMQ3

PGEQ4

GLUCONATEQ4

RATQ4

Abstract

Aim: The quantity of ROOT RESORPTION was measured after injections ofPGE2 alone and with CALCIUM GLUCONATE during orthodontic tooth movement.Materials & Method: A group of 24, male Wistar RATs, 8 week - old were randomly placed into 3 groups.Orthodontic appliance consisted of a Closed Coil Spring ligated to the first upper right molar and incisor of the same side, applying a 60-gr force. The control group had localized injections of distilled water on the buccal gingiva of the upper right first molar. In the second experimental group, 0.1 ml of Imgr/ml PGE2 was injected at the same place, while the third group received IP injection of 200mg/kg CALCIUM GLUCONATE (10%) beside the PGE2. All injections were performed on day 1 and 7. Animals were sacrificed on the day 21. Palatal halves of both sides in the Control group (right side as control and left side as normal) were removed for histological process with the right palatal halves of the other groups. ROOT RESORPTION was calculated on the mesial root surface of the right molar by sum of the resorptive surfaces, multiplying the deepest depth and the Largest Length of the resorptive surfaces. The data were analysed by Kruskal- Wallis and Multiple Range tests.Results: There were no statistically significant differences between the 4 groups, except for the normal group and the PGE2 group. PGE2 as a mediator of orthodontic movement, enhanced the ROOT RESORPTION following the remodeling process in respect to the teeth that were not moved orthodontically. Conclusion: The judicious use of local and systemic biochemical agents which alter remodeling of periodontal tissues, in conjunction with orthodontic treatment appears to have less side effects during the treatment. Transient systemic hypoparathy roidism following the CALCIUM content injections seemed to decrease the trend towards ROOT RESORPTION in comparison to PGE2 group.

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APA: Copy

SEYFI, M., & ESLAMI, B.. (2002). THE EFFECT OF PGE2 AND CALCIUM GLUCONATE ON ROOT RESORPTION IN RATS. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 20(3), 316-321. SID. https://sid.ir/paper/22256/en

Vancouver: Copy

SEYFI M., ESLAMI B.. THE EFFECT OF PGE2 AND CALCIUM GLUCONATE ON ROOT RESORPTION IN RATS. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2002;20(3):316-321. Available from: https://sid.ir/paper/22256/en

IEEE: Copy

M. SEYFI, and B. ESLAMI, “THE EFFECT OF PGE2 AND CALCIUM GLUCONATE ON ROOT RESORPTION IN RATS,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 20, no. 3, pp. 316–321, 2002, [Online]. Available: https://sid.ir/paper/22256/en

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