DETERMINATION OF THE DIAGNOSTIC VALUE OF SERUM AMYLOID A, HAPTOGLOBIN AND SOME HEMATOLOGIC PARAMETERS IN ASSESSMENT OF HORSE HEALTH

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MORTAZAVI S.M.; SAFI S.; SHIRAZI BEHESHTIHA S.H.; RABBANI V.

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Journal: JOURNAL OF VETERINARY CLINICAL RESEARCH Year:2012 | Volume:3 | Issue:2 (10) Page(s): 63-73

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Title

DETERMINATION OF THE DIAGNOSTIC VALUE OF SERUM AMYLOID A, HAPTOGLOBIN AND SOME HEMATOLOGIC PARAMETERS IN ASSESSMENT OF HORSE HEALTH

Author(s)

MORTAZAVI S.M. | SAFI S. | SHIRAZI BEHESHTIHA S.H. | RABBANI V. | Issue Writer Certificate

Keywords

SERUM AMYLOID AQ2

HAPTOGLOBINQ2

HORSEQ1

HEALTHQ2

Abstract

Acute Phase Proteins (APPs) are a class of serum proteins whose their concentration increase remarkably in response to infections, inflammation, trauma, neoplasia and etc. HAPTOGLOBIN (HPt) and SERUM AMYLOID A (SAA) are two major APPs in HORSE. Since, in farms, differentiation between HEALTHy and sick HORSE is so important, the present study was designed to determine the diagnostic value of APPs as sensitive biomarkers, and compare it with hematologic parameters for differentiation of HEALTHy and sick HORSEs in farm. According to the results of the present study, increase in the median of HPt and SAA was significant. With regard to the ROC curve, cutoff point of HPt and SAA was 0.829 and 0.6 ng/dl respectively and sensitivity and specificity in their cut off point was 86%, 87% for Hpt and 84 %, 73% for SAA In addition, Clinical Accuracy of HPt and SAA, base of area under the curve, was 0907, 0.891 respectively, In other hand, Significant difference between the clinical accuracy of HPt and SAA has not be seen, Results of the present study show that HPt and SAA measurement can be used as a screening test to determine HEALTH status in HORSE.

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APA: Copy

MORTAZAVI, S.M., SAFI, S., SHIRAZI BEHESHTIHA, S.H., & RABBANI, V.. (2012). DETERMINATION OF THE DIAGNOSTIC VALUE OF SERUM AMYLOID A, HAPTOGLOBIN AND SOME HEMATOLOGIC PARAMETERS IN ASSESSMENT OF HORSE HEALTH. JOURNAL OF VETERINARY CLINICAL RESEARCH, 3(2 (10)), 63-73. SID. https://sid.ir/paper/233067/en

Vancouver: Copy

MORTAZAVI S.M., SAFI S., SHIRAZI BEHESHTIHA S.H., RABBANI V.. DETERMINATION OF THE DIAGNOSTIC VALUE OF SERUM AMYLOID A, HAPTOGLOBIN AND SOME HEMATOLOGIC PARAMETERS IN ASSESSMENT OF HORSE HEALTH. JOURNAL OF VETERINARY CLINICAL RESEARCH[Internet]. 2012;3(2 (10)):63-73. Available from: https://sid.ir/paper/233067/en

IEEE: Copy

S.M. MORTAZAVI, S. SAFI, S.H. SHIRAZI BEHESHTIHA, and V. RABBANI, “DETERMINATION OF THE DIAGNOSTIC VALUE OF SERUM AMYLOID A, HAPTOGLOBIN AND SOME HEMATOLOGIC PARAMETERS IN ASSESSMENT OF HORSE HEALTH,” JOURNAL OF VETERINARY CLINICAL RESEARCH, vol. 3, no. 2 (10), pp. 63–73, 2012, [Online]. Available: https://sid.ir/paper/233067/en

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