EFFECT OF FLUNIXIN MEGLUMINE INJECTION ON CONCEPTION RATE AND PLASMA PROGESTERONE CHANGES IN HOLSTEIN HEIFERS

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ROOSTAIE M.; YADI J.; SAEED KHALAJZADEH S.

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Journal: JOURNAL OF VETERINARY CLINICAL RESEARCH Year:2012 | Volume:3 | Issue:1 (9) Page(s): 35-40

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Title

EFFECT OF FLUNIXIN MEGLUMINE INJECTION ON CONCEPTION RATE AND PLASMA PROGESTERONE CHANGES IN HOLSTEIN HEIFERS

Author(s)

ROOSTAIE M. | YADI J. | SAEED KHALAJZADEH S. | Issue Writer Certificate

Keywords

FLUNIXIN MEGLUMINEQ2

PGF2αQ2

CONCEPTION RATEQ3

PROGESTERONEQ2

OVSYNCHQ2

Abstract

The objective of this study was to examine the effects of administration of FLUNIXIN MEGLUMINE on CONCEPTION RATEs and plasma PROGESTERONE (P4) changes in Holstein heifers and inhibition of PGF2a synthesis just before luteolysis. 32 Holstein heifers (15-month-old, BW: 357±5kg) Were Synchronized utilizing OVSYNCH protocol and artificially inseminated. The heifers were assigned randomly to a treatment group (n=16) and a control group (n=16). The treatment groups were injected intramuscularly three times on days 15.5, 16 and 16.5 post insemination with 1.1 mg/kg bodyweight FLUNIXIN MEGLUMINE whereas control group received placebo. Blood samples were collected on days 15.5, 16 and 16.5 post insemination for analysis of plasma P4 concentrations. Pregnancy was diagnosed on days 30 and 60 by transrectal ultrasonography. On day 30, 10 of the treated heifers were pregnant compared with 4 of the control heifers (P<0.05); on day 60, 9 of the treated heifers were still pregnant compared with 4 of the control heifers (P>0.05). Mean plasma PROGESTERONE concentrations on day 16.5 in treated heifers (2.62±0.66 ng/ml-1) was higher than control group (1.87±1 ng/ml-1) but this improvement was not statistically significant (P>0.1). The results of this study support the hypothesis that FLUNIXIN MEGLUMINE is able to inhibit the uterine synthesis of PGF2a and increase the survival of early embryos.

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APA: Copy

ROOSTAIE, M., YADI, J., & SAEED KHALAJZADEH, S.. (2012). EFFECT OF FLUNIXIN MEGLUMINE INJECTION ON CONCEPTION RATE AND PLASMA PROGESTERONE CHANGES IN HOLSTEIN HEIFERS. JOURNAL OF VETERINARY CLINICAL RESEARCH, 3(1 (9)), 35-40. SID. https://sid.ir/paper/233083/en

Vancouver: Copy

ROOSTAIE M., YADI J., SAEED KHALAJZADEH S.. EFFECT OF FLUNIXIN MEGLUMINE INJECTION ON CONCEPTION RATE AND PLASMA PROGESTERONE CHANGES IN HOLSTEIN HEIFERS. JOURNAL OF VETERINARY CLINICAL RESEARCH[Internet]. 2012;3(1 (9)):35-40. Available from: https://sid.ir/paper/233083/en

IEEE: Copy

M. ROOSTAIE, J. YADI, and S. SAEED KHALAJZADEH, “EFFECT OF FLUNIXIN MEGLUMINE INJECTION ON CONCEPTION RATE AND PLASMA PROGESTERONE CHANGES IN HOLSTEIN HEIFERS,” JOURNAL OF VETERINARY CLINICAL RESEARCH, vol. 3, no. 1 (9), pp. 35–40, 2012, [Online]. Available: https://sid.ir/paper/233083/en

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