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Title

SAFETY AND EFFICACY OF INCREASING SERUM VITAMIN D BY MILK FORTIFICATION

Pages

  27-38

Abstract

 Objective(s): Deficiencies in calcium and VITAMIN D intakes are involved in the etiology of osteoporosis, and health authorities recommend that the population consume a diet providing sufficient calcium and VITAMIN D. We studied the safety and efficacy of MILK fortified with VITAMIN D3. Methods: We conducted a double-blind, placebo-controlled trial of fortified MILK (600 IU/l VITAMIN D3) compared to unfortified MILK in 216 subjects (aged 2-98 years). Serum 25-hydroxyVITAMIN D [25(OH)D], calcium, creatinine, PTH were measured at baseline and after intervention. 109 subjects ingested 400 mL fortified MILK with 240 IU VITAMIN D, and 107 subjects ingested a control MILK daily for 8 wk.Results: After subjects consumed fortified MILK for 8 wk, serum 25(OH) D3 concentrations increased by 33%, and serum parathyroid hormone concentrations decreased by 40% compared with baseline; control subjects had a decrease of 7% in 25(OH)D and no significant change in serum parathyroid hormone. In the fortified group, serum 25(OH)D increased by 13 nmol/l from 39.94 nmol/l to 53.37 nmol/l . In the control group, serum 25(OH)D felt by 3 nmol/l from 43.11 nmol/l to 39.9 nmol/l. Conclusion: VITAMIN D-fortified MILK may assist in maintaining VITAMIN D status in the general population.

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APA: Copy

ARDESHIR LARIJANI, MOHAMMAD BAGHER, SHEYKH AL ESLAMI, R., ADIBI, H., SHAFAEI, A., MAGHBOOLI, Z., MOHAMMADZADEH, N., & HOSSEINNEZHAD, ARASH. (2004). SAFETY AND EFFICACY OF INCREASING SERUM VITAMIN D BY MILK FORTIFICATION. PAYESH, 3(1), 27-38. SID. https://sid.ir/paper/23534/en

Vancouver: Copy

ARDESHIR LARIJANI MOHAMMAD BAGHER, SHEYKH AL ESLAMI R., ADIBI H., SHAFAEI A., MAGHBOOLI Z., MOHAMMADZADEH N., HOSSEINNEZHAD ARASH. SAFETY AND EFFICACY OF INCREASING SERUM VITAMIN D BY MILK FORTIFICATION. PAYESH[Internet]. 2004;3(1):27-38. Available from: https://sid.ir/paper/23534/en

IEEE: Copy

MOHAMMAD BAGHER ARDESHIR LARIJANI, R. SHEYKH AL ESLAMI, H. ADIBI, A. SHAFAEI, Z. MAGHBOOLI, N. MOHAMMADZADEH, and ARASH HOSSEINNEZHAD, “SAFETY AND EFFICACY OF INCREASING SERUM VITAMIN D BY MILK FORTIFICATION,” PAYESH, vol. 3, no. 1, pp. 27–38, 2004, [Online]. Available: https://sid.ir/paper/23534/en

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