THERAPEUTIC INDICES IN THALASSEMIA MAJOR: ASSOCIATION WITH BONE MINERAL DENSITY

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ARDESHIR LARIJANI MOHAMMAD BAGHER; BEKHEIRNIA M.R.; KAMGAR M.; MORADI ZIRKUHI A.; ERFANZADEH G.; BOUZARI N.; TABATABAEI S.M.; ABD ELAH SHAMSHIRSAZ A.R.; ABDOLLAH SHAMSHIRSAZ A.H.

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Journal: Payesh Year:2004 | Volume:3 | Issue:1 Page(s): 75-81

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Title

THERAPEUTIC INDICES IN THALASSEMIA MAJOR: ASSOCIATION WITH BONE MINERAL DENSITY

Author(s)

Keywords

THALASSEMIA MAJORQ3

BONE MASS DENSITYQ4

THERAPEUTIC INDICESQ3

GROWTHQ3

Abstract

Objective(s): To evaluate bone mineral density (BMD) in children and young adults with thalassemia and its potential risk factors. Methods: Two hundreds and twelve thalassemic patients aged 10-20 were enrolled in the study. In all patients height, weight, body mass index, GROWTH indices, pubertal development, calcium intake and serum ferritin were assessed. BMD was determined by dual-energy X-ray absorptiometry (Lunar). BMD z scores between -1 and -2.5 were identified as low bone mass and z scores less than -2.5 were considered severely low bone mass. Results: Prevalence of severely low bone mass was 50.7% in lumbar spine, 10.8% in femur and 7.9% in both areas. There was no statistically significant between males and females. Low bone mass was observed in 39.5% and 37.5% of patients in lumbar and femoral areas. Patients with severely low bone mass in lumbar spine were older than the others (P<0.001). Conclusion: The data confirm significant reductions in BMD in Iranian thalassemic patients. Further research is needed to identify risk factors and preventive methods recommend.

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APA: Copy

ARDESHIR LARIJANI, MOHAMMAD BAGHER, BEKHEIRNIA, M.R., KAMGAR, M., MORADI ZIRKUHI, A., ERFANZADEH, G., BOUZARI, N., TABATABAEI, S.M., ABD ELAH SHAMSHIRSAZ, A.R., & ABDOLLAH SHAMSHIRSAZ, A.H.. (2004). THERAPEUTIC INDICES IN THALASSEMIA MAJOR: ASSOCIATION WITH BONE MINERAL DENSITY. PAYESH, 3(1), 75-81. SID. https://sid.ir/paper/23537/en

Vancouver: Copy

ARDESHIR LARIJANI MOHAMMAD BAGHER, BEKHEIRNIA M.R., KAMGAR M., MORADI ZIRKUHI A., ERFANZADEH G., BOUZARI N., TABATABAEI S.M., ABD ELAH SHAMSHIRSAZ A.R., ABDOLLAH SHAMSHIRSAZ A.H.. THERAPEUTIC INDICES IN THALASSEMIA MAJOR: ASSOCIATION WITH BONE MINERAL DENSITY. PAYESH[Internet]. 2004;3(1):75-81. Available from: https://sid.ir/paper/23537/en

IEEE: Copy

MOHAMMAD BAGHER ARDESHIR LARIJANI, M.R. BEKHEIRNIA, M. KAMGAR, A. MORADI ZIRKUHI, G. ERFANZADEH, N. BOUZARI, S.M. TABATABAEI, A.R. ABD ELAH SHAMSHIRSAZ, and A.H. ABDOLLAH SHAMSHIRSAZ, “THERAPEUTIC INDICES IN THALASSEMIA MAJOR: ASSOCIATION WITH BONE MINERAL DENSITY,” PAYESH, vol. 3, no. 1, pp. 75–81, 2004, [Online]. Available: https://sid.ir/paper/23537/en

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