THE EFFECTS OF ETHANOL EXTRACT OF ALHAGI CAMELORUM ON HEPATIC AND RENAL FUNCTIONS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

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NABIYOUNI FATEMEH; VAEZI GHOLAMHASAN; MALEKIRAD ALI AKBAR; ABDOLLAHI MOHAMMAD

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Journal: EXPERIMENTAL ANIMAL BIOLOGY Year:2016 | Volume:5 | Issue:1 (17) Page(s): 31-38

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Title

THE EFFECTS OF ETHANOL EXTRACT OF ALHAGI CAMELORUM ON HEPATIC AND RENAL FUNCTIONS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Author(s)

NABIYOUNI FATEMEH | VAEZI GHOLAMHASAN | MALEKIRAD ALI AKBAR | ABDOLLAHI MOHAMMAD | Issue Writer Certificate

Keywords

DIABETESQ2

LIVERQ2

KIDNEYQ2

ALHAGI CAMELORUMQ1

STREPTOZOTOCINQ1

Abstract

DIABETES is one of the most common metabolic diseases and in the long term affects many parts of body, including LIVER and KIDNEYs. This study was to investigate alcoholic extract effect of Alhagi camelo rum on functional tests of LIVER and KIDNEY in diabetic rats induced by STREPTOZOTOCIN. In this study, 28 Wistar male rats were divided into the four groups (n=7): non-diabetic control group received normal diet, diabetic group was induced by STREPTOZOTOCIN and received 1ml of normal saline daily as extract solvent, two diabetic experimental groups received alcoholic extract of Alhagi Camelo rum at dose of 200 mg/kg and 300 mg/kg by gavage, respectively. To induce DIABETES, STREPTOZOTOCIN was injected to rats intraperitoneally at dose of 50 mg/kg. Blood samples were collected at day 21 from all groups and the related blood factors were measured and analyzed by SPSS (ANOVA). The findings show that there was a significant increase in creatinine, urea levels and LIVER enzymes in diabetic control group when compared to the non-diabetic control group. While the same amount factors show decrease in the groups receiving alcoholic extract of Alhagi Camerolum. The results show that alcoholic extract of aerial parts of Alhagi Camerolum causes to the decreased creatinine, urea levels and LIVER enzymes.

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APA: Copy

NABIYOUNI, FATEMEH, VAEZI, GHOLAMHASAN, MALEKIRAD, ALI AKBAR, & ABDOLLAHI, MOHAMMAD. (2016). THE EFFECTS OF ETHANOL EXTRACT OF ALHAGI CAMELORUM ON HEPATIC AND RENAL FUNCTIONS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS. EXPERIMENTAL ANIMAL BIOLOGY, 5(1 (17)), 31-38. SID. https://sid.ir/paper/236141/en

Vancouver: Copy

NABIYOUNI FATEMEH, VAEZI GHOLAMHASAN, MALEKIRAD ALI AKBAR, ABDOLLAHI MOHAMMAD. THE EFFECTS OF ETHANOL EXTRACT OF ALHAGI CAMELORUM ON HEPATIC AND RENAL FUNCTIONS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS. EXPERIMENTAL ANIMAL BIOLOGY[Internet]. 2016;5(1 (17)):31-38. Available from: https://sid.ir/paper/236141/en

IEEE: Copy

FATEMEH NABIYOUNI, GHOLAMHASAN VAEZI, ALI AKBAR MALEKIRAD, and MOHAMMAD ABDOLLAHI, “THE EFFECTS OF ETHANOL EXTRACT OF ALHAGI CAMELORUM ON HEPATIC AND RENAL FUNCTIONS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS,” EXPERIMENTAL ANIMAL BIOLOGY, vol. 5, no. 1 (17), pp. 31–38, 2016, [Online]. Available: https://sid.ir/paper/236141/en

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