Nucleic Acid Aptamers: New Tools in Diagnosis and Therapy

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GHASEMI D.; Farokhi Fard a.; SANKIAN M.

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Paper Information

Journal: Journal of Paramedical Science and Rehabilitation Year:2019 | Volume:7 | Issue:4 Page(s): 100-113

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Information Journal Paper

Title

Nucleic Acid Aptamers: New Tools in Diagnosis and Therapy

Author(s)

GHASEMI D. | Farokhi Fard a. | SANKIAN M. | Issue Writer Certificate

Keywords

Nucleic acid aptamerQ1

AntibodyQ1

Aptamer selectionQ1

PegaptanibQ1

Abstract

Aptamers are short single-stranded nucleotides (or peptide) folded into particular three-dimensional structure which can bind to their targets with high specificity and affinity. Small size, inexpensive and rapid production process, low immunogenicity and high stability, made them very attractive biomolecules in some investigational fields especially in planning of innovative diagnostic and therapeutic approaches. In this review, we have described the process of Nucleic acid aptamers development, advantages and disadvantages of aptamers compared to antibodies, and potential applications of these new agents in medicine. Limitations of aptamers and existing answers to overcome this limitations has also been discussed.

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References

Replacing antibodies with modified DNA aptamers in vaccine potency assays

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APA: Copy

GHASEMI, D., Farokhi Fard, a., & SANKIAN, M.. (2019). Nucleic Acid Aptamers: New Tools in Diagnosis and Therapy. JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR), 7(4 ), 100-113. SID. https://sid.ir/paper/245360/en

Vancouver: Copy

GHASEMI D., Farokhi Fard a., SANKIAN M.. Nucleic Acid Aptamers: New Tools in Diagnosis and Therapy. JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR)[Internet]. 2019;7(4 ):100-113. Available from: https://sid.ir/paper/245360/en

IEEE: Copy

D. GHASEMI, a. Farokhi Fard, and M. SANKIAN, “Nucleic Acid Aptamers: New Tools in Diagnosis and Therapy,” JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR), vol. 7, no. 4 , pp. 100–113, 2019, [Online]. Available: https://sid.ir/paper/245360/en

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