COMPARISON OF ACCURACY OF MACHINE LEARNING ALGORITHMS ON MISSING VALUES ESTIMATION OF DNA MICROARRAY DATASETS

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MOSHIRY M.; GHADERI ZEFREHEI M.; GHANE GOLMOHAMMADI F.

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Journal: Journal of Molecular and Cellular Researches Year:2015 | Volume:28 | Issue:4 Page(s): 612-622

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Title

COMPARISON OF ACCURACY OF MACHINE LEARNING ALGORITHMS ON MISSING VALUES ESTIMATION OF DNA MICROARRAY DATASETS

Author(s)

MOSHIRY M. | GHADERI ZEFREHEI M. | GHANE GOLMOHAMMADI F. | Issue Writer Certificate

Keywords

MACHINE LEARNING ALGORITHMSQ2

MISSING VALUE ESTIMATIONQ2

MICROARRAYQ1

Abstract

Presence of missing values in MICROARRAY data decreases accuracy of drawing regulatory gene networks and may cause mistake in clustering and specialized classification of genes and further analysis. Therefore, missing values estimation is one of the most important steps in preprocessing of MICROARRAY data. Function of estimation algorithms is varied in different datasets and different missing percentage. Select a proper algorithm, in order to achieve the most accurate results in calculation of missing values, is a critical point. In this study, three MICROARRAY datasets were used. Dimensions of expression matrix was determined, and data normalization was carried out, then, different missing percentages were applied on under studied datasets.11 MACHINE LEARNING ALGORITHMS were used to estimate the missing values, and their accuracy were compaied based on the output. Based on the archeived results, accuracy of each algorithms depends on used datasets, missing percentage, and missing distribution. Also, the number of experimental samples in datasets can affect the accuracy of missing values estimation algorithms. The results revealed a descending trend in accuracy over increasing the percentage of missing data. However, Least Square Adaptive and Local Least Square algorithms showed more accuracy through increasing of missing percentage rather than others.

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APA: Copy

MOSHIRY, M., GHADERI ZEFREHEI, M., & GHANE GOLMOHAMMADI, F.. (2015). COMPARISON OF ACCURACY OF MACHINE LEARNING ALGORITHMS ON MISSING VALUES ESTIMATION OF DNA MICROARRAY DATASETS. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), 28(4), 612-622. SID. https://sid.ir/paper/248572/en

Vancouver: Copy

MOSHIRY M., GHADERI ZEFREHEI M., GHANE GOLMOHAMMADI F.. COMPARISON OF ACCURACY OF MACHINE LEARNING ALGORITHMS ON MISSING VALUES ESTIMATION OF DNA MICROARRAY DATASETS. JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY)[Internet]. 2015;28(4):612-622. Available from: https://sid.ir/paper/248572/en

IEEE: Copy

M. MOSHIRY, M. GHADERI ZEFREHEI, and F. GHANE GOLMOHAMMADI, “COMPARISON OF ACCURACY OF MACHINE LEARNING ALGORITHMS ON MISSING VALUES ESTIMATION OF DNA MICROARRAY DATASETS,” JOURNAL OF MOLECULAR AND CELLULAR RESEARCH (IRANIAN JOURNAL OF BIOLOGY), vol. 28, no. 4, pp. 612–622, 2015, [Online]. Available: https://sid.ir/paper/248572/en

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