ASSOCIATION BETWEEN GENE POLYMORPHISM RS11614913 IN MICRORNA196A2, WITH NON-SMALL CELL LUNG CANCER RISK IN THE POPULATION OF SOUTHERN IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

PISHVA PARVIN; TAHMASEB MOHAMMAD; GHADERI ABBAS

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: NOVA BIOLOGICA REPERTA Year:2016 | Volume:3 | Issue:1 Page(s): 15-23

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

874

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION BETWEEN GENE POLYMORPHISM RS11614913 IN MICRORNA196A2, WITH NON-SMALL CELL LUNG CANCER RISK IN THE POPULATION OF SOUTHERN IRAN

Author(s)

PISHVA PARVIN | TAHMASEB MOHAMMAD | GHADERI ABBAS | Issue Writer Certificate

Keywords

MICRO RNAQ2

NON-SMALL CELL LUNG CANCERQ1

SNPQ1

Abstract

Lung cancer is the fifth most common cancer in Iran, with rates of 4.7 to 9.2 per 100 thousand populations. Despite the low incidence, survival is not promising. Using biological markers could lead to longer survival rate in patients due to early diagnosis. In this study, we evaluated the association of SNP rs11614913 in mir-196a2 with risk of NON-SMALL CELL LUNG CANCER (NSCLC) in population of southern Iran. SNP rs11614913 in miR-196a2 was assayed in 95 lung cancer patients and 100 controls. The extracted DNA from peripheral blood was amplified using specific primers followed by TaaI digestion. Based on the nucleotide base in this SNP (T or C) two different patterns were produced. In case of T, two bands (187bp and 196bp) and in case of C just one band (383bp) was generated. Analysis of electrophoretic pattern of digestion products revealed that the frequencies of C allele for SNP rs11614913 miR-196a2 were 0.695 in patients and 0.76 in controls. The statistical analysis indicates the presence of Hardy-Weinberg equilibrium between the two alleles in the population studied (p>0.05). Based on the results in this study, no significant association between SNP rs11614913 and susceptibility to NSCLC was found. However, male participants who possess TC/TT genotypes showed high risk for NSCLC compared to those possessed CC genotypes.

Cites

No record.

References

No record.

Cite

APA: Copy

PISHVA, PARVIN, TAHMASEB, MOHAMMAD, & GHADERI, ABBAS. (2016). ASSOCIATION BETWEEN GENE POLYMORPHISM RS11614913 IN MICRORNA196A2, WITH NON-SMALL CELL LUNG CANCER RISK IN THE POPULATION OF SOUTHERN IRAN. NOVA BIOLOGICA REPERTA, 3(1), 15-23. SID. https://sid.ir/paper/250506/en

Vancouver: Copy

PISHVA PARVIN, TAHMASEB MOHAMMAD, GHADERI ABBAS. ASSOCIATION BETWEEN GENE POLYMORPHISM RS11614913 IN MICRORNA196A2, WITH NON-SMALL CELL LUNG CANCER RISK IN THE POPULATION OF SOUTHERN IRAN. NOVA BIOLOGICA REPERTA[Internet]. 2016;3(1):15-23. Available from: https://sid.ir/paper/250506/en

IEEE: Copy

PARVIN PISHVA, MOHAMMAD TAHMASEB, and ABBAS GHADERI, “ASSOCIATION BETWEEN GENE POLYMORPHISM RS11614913 IN MICRORNA196A2, WITH NON-SMALL CELL LUNG CANCER RISK IN THE POPULATION OF SOUTHERN IRAN,” NOVA BIOLOGICA REPERTA, vol. 3, no. 1, pp. 15–23, 2016, [Online]. Available: https://sid.ir/paper/250506/en

Related Journal Papers