STUDY OF ANTIBACTERIAL AND SYNERGISTIC EFFECT OF DIGITALIS NERVOSA EXTRACT AND CIPROFLOXACIN ON STAPHYLOCOCCUS AUREUS

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AYOUBINEJAD L.; NAZARI H.; MOHAMMADI SANI A.

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Journal: JOURNAL OF FOOD MICROBIOLOGY Year:2016 | Volume:3 | Issue:1 Page(s): 25-31

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Title

STUDY OF ANTIBACTERIAL AND SYNERGISTIC EFFECT OF DIGITALIS NERVOSA EXTRACT AND CIPROFLOXACIN ON STAPHYLOCOCCUS AUREUS

Author(s)

AYOUBINEJAD L. | NAZARI H. | MOHAMMADI SANI A. | Issue Writer Certificate

Keywords

ETHANOL EXTRACTQ1

ANTIBACTERIALQ2

DIGITALIS NERVOSAQ1

CIPROFLOXACINQ3

SYNERGISTIC EFFECTQ1

Abstract

In spite of novel progresses in the methods for foodstuff’s preparation and production, consumer’s health and safety in the public hygiene import increasingly. One of the ways to control pathogenic microorganisms is the use of chemical preservatives in food. This study was done for determining ANTIBACTERIAL effects of DIGITALIS NERVOSA extracts on Staphylococcus aureus pathogenic bacteria. In this study the ANTIBACTERIAL effects of ethanolic extract of D. nervosa alone and in combination with CIPROFLOXACIN were evaluated on gram-positive bacteria, S. aureus (ATCC25923), by micro broth dilution method. MIC test results for D. nervosa extract and CIPROFLOXACIN were 4.9 and 0.5 mg/ml, respectively. Combined effects of antibiotic and the extract revealed that S. aureus was inhibited by the ethanolic extract and CIPROFLOXACIN respectively at 3.5 and 0.28 mg/ml. MBC were measured 7.1 and 1 mg/ml respectively against ethanolic extract and CIPROFLOXACIN. Simultaneous application of the extract at 1 mg/ml and CIPROFLOXACIN at 0.14 mg/ml destroyed S. aureus. Results showed that simultaneous use of alcoholic extract and CIPROFLOXACIN, reduced antibiotic usage by 48% to inhibit S. aureus and also the concomitant use of alcoholic extract and antibiotic, caused 86% reduction in antibiotic use to reach MBC point against S. aureus.

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APA: Copy

AYOUBINEJAD, L., NAZARI, H., & MOHAMMADI SANI, A.. (2016). STUDY OF ANTIBACTERIAL AND SYNERGISTIC EFFECT OF DIGITALIS NERVOSA EXTRACT AND CIPROFLOXACIN ON STAPHYLOCOCCUS AUREUS. JOURNAL OF FOOD MICROBIOLOGY, 3(1), 25-31. SID. https://sid.ir/paper/250789/en

Vancouver: Copy

AYOUBINEJAD L., NAZARI H., MOHAMMADI SANI A.. STUDY OF ANTIBACTERIAL AND SYNERGISTIC EFFECT OF DIGITALIS NERVOSA EXTRACT AND CIPROFLOXACIN ON STAPHYLOCOCCUS AUREUS. JOURNAL OF FOOD MICROBIOLOGY[Internet]. 2016;3(1):25-31. Available from: https://sid.ir/paper/250789/en

IEEE: Copy

L. AYOUBINEJAD, H. NAZARI, and A. MOHAMMADI SANI, “STUDY OF ANTIBACTERIAL AND SYNERGISTIC EFFECT OF DIGITALIS NERVOSA EXTRACT AND CIPROFLOXACIN ON STAPHYLOCOCCUS AUREUS,” JOURNAL OF FOOD MICROBIOLOGY, vol. 3, no. 1, pp. 25–31, 2016, [Online]. Available: https://sid.ir/paper/250789/en

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