ASSOCIATION OF OX-LDL AND MDA SERUM LEVEL WITH EXTENT OF CORONARY ARTERY DISEASE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHAKI KHATIBI F.; MAHMOODI N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Alborz University Medical Journal Year:2016 | Volume:5 | Issue:4 Page(s): 229-235

Download Full-Text

Persian Verion

View:

761

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION OF OX-LDL AND MDA SERUM LEVEL WITH EXTENT OF CORONARY ARTERY DISEASE

Author(s)

KHAKI KHATIBI F. | MAHMOODI N. | Issue Writer Certificate

Keywords

OXIDIZED LDLQ1

MALONDIALDEHYDEQ2

CORONARY ARTERY DISEASEQ3

Abstract

Background: Atherosclerosis is the main reason of CORONARY ARTERY DISEASE (CAD). The studies show that several factors are interconnected with the development and progression of CAD including lipid peroxidation, inflammation and homeostasis. The aim of this study was to evaluate the serum level of OXIDIZED LDL (OX-LDL) and MALONDIALDEHYDE (MDA) and their association with the extent of CORONARY ARTERY DISEASE.Methods: In this cross-sectional study serum OX-LDL and MDA levels were determined in 160 patients with CORONARY ARTERY DISEASE comprised of 40 subjects with no vessel disease, 40 subjects with single vessel disease, 40 subjects with double vessel disease, and 40 subjects with triple vessel disease matched control healthy 20 subjects. Serum levels of OX-LDL determined used to (ELISA) procedure. Serum level of MDA was measured by photometric method based on reaction with Thiobarbituric Acid (TBA). Data were analyzed using Spearman correlation coefficients, Student's t test or ANOVA.Result: OXIDIZED LDL and MALONDIALDEHYDE serum levels in patient groups were significantly higher than control groups (p<0.05). Furthermore, serum concentrations of OX-LDL in double-vessel disease were significantly higher as compare with control and no-vessel groups and triple vessel disease were significantly higher as compare with single vessel disease (p<0.05). Serum concentrations of MDA in double-vessel disease were significantly higher as compare with control and no-vessel groups and triple vessel disease were significantly higher as compare with single vessel disease (p<0.05).Conclusion: Elevated serum levels of OX-LDL and MDA indicate potential role in atherogenesis leading to CAD. There for our findings suggest that determination of serum OX-LDL and MDA levels can be useful as diagnostic and monitoring markers in patients with CAD and its extent.

Cites

No record.

References

No record.

Cite

APA: Copy

KHAKI KHATIBI, F., & MAHMOODI, N.. (2016). ASSOCIATION OF OX-LDL AND MDA SERUM LEVEL WITH EXTENT OF CORONARY ARTERY DISEASE. ALBORZ UNIVERSITY MEDICAL JOURNAL, 5(4), 229-235. SID. https://sid.ir/paper/254406/en

Vancouver: Copy

KHAKI KHATIBI F., MAHMOODI N.. ASSOCIATION OF OX-LDL AND MDA SERUM LEVEL WITH EXTENT OF CORONARY ARTERY DISEASE. ALBORZ UNIVERSITY MEDICAL JOURNAL[Internet]. 2016;5(4):229-235. Available from: https://sid.ir/paper/254406/en

IEEE: Copy

F. KHAKI KHATIBI, and N. MAHMOODI, “ASSOCIATION OF OX-LDL AND MDA SERUM LEVEL WITH EXTENT OF CORONARY ARTERY DISEASE,” ALBORZ UNIVERSITY MEDICAL JOURNAL, vol. 5, no. 4, pp. 229–235, 2016, [Online]. Available: https://sid.ir/paper/254406/en

Related Journal Papers