Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Pos t-Traumatic Stress Disorder in Veterans

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Sarhadi Shabnam; GHAEMI FATEMEH; DORTAJ FARIBORZ; DELAVAR ALI

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Journal: Neuroscience Journal of Shefaye Khatam Year:2020 | Volume:8 | Issue:1 Page(s): 51-62

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Title

Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Pos t-Traumatic Stress Disorder in Veterans

Author(s)

Sarhadi Shabnam | GHAEMI FATEMEH | DORTAJ FARIBORZ | DELAVAR ALI | Issue Writer Certificate

Keywords

Transcranial Direct Current StimulationQ1

SertralineQ1

VeteransQ2

Combat DisordersQ1

Abstract

Introduction: Traumatic Stress Disorder (PTSD) is one of the mos t prevalent health problems in the victims of the Iran-Iraq war. Despite many advantages of the adminis tration of selective serotonin reuptake inhibitors, as the firs t-line treatment of PTSD, a large number of the patients s till need more effective therapies. The purpose of this s tudy was to comparison of the effectiveness of Sertraline, transcranial direct s timulation current (TDCS), and the combined treatment (TDCS and Sertraline) to relieve the symptoms of PTSD in the Veterans in Tehran, Iran. Materials and Methods: The current s tudy was a semi-experimental s tudy including pre-and pos t-tes ts, a control group, and three-month follow-up. The population of s tudy was Veterans who lived in Tehran in 2018. 68 Veterans were selected by purposive sampling method and then randomly divided to control and experimental groups. The firs tgroup was treated with Sertraline, the second group received TDCS, and the third group treated with the combined treatment. The PTSD Checklis t for DSM-5(PCL-5) was used as a research tool. Results: All of the treatment approaches were effective in reduction of symptoms in patients with PTSD. In the pos t-tes t and follow-up phase, there was a significant difference in PCL-5 scores between Sertraline, TDCS, and combined treatment in comparison with the control group. Combined treatment (TDCS and Sertraline) have shown a significantly higher and persis tence effectiveness. Conclusion: Combined treatment with TDCS and Sertraline can be used as an efficient and effective approach to reduce PTSD symptoms in Veterans.

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APA: Copy

Sarhadi, Shabnam, GHAEMI, FATEMEH, DORTAJ, FARIBORZ, & DELAVAR, ALI. (2020). Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Pos t-Traumatic Stress Disorder in Veterans. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 8(1 ), 51-62. SID. https://sid.ir/paper/257944/en

Vancouver: Copy

Sarhadi Shabnam, GHAEMI FATEMEH, DORTAJ FARIBORZ, DELAVAR ALI. Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Pos t-Traumatic Stress Disorder in Veterans. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2020;8(1 ):51-62. Available from: https://sid.ir/paper/257944/en

IEEE: Copy

Shabnam Sarhadi, FATEMEH GHAEMI, FARIBORZ DORTAJ, and ALI DELAVAR, “Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Pos t-Traumatic Stress Disorder in Veterans,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 8, no. 1 , pp. 51–62, 2020, [Online]. Available: https://sid.ir/paper/257944/en

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