STUDIES OF THE INTERACTION OF NI (II) COMPLEXES BEARING PLANAR AROMATIC LIGANDS WITH CALF THYMUS DNA

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ESMAEILZAEI ZOHREH; SABOURY AIL AKBAR; MANSOURI TORSHIZI HASAN; SAEIDIFAR MARYAM; DIVSALAR ADELEH

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Journal: Nashrieh Shimi va Mohandesi Shimi Iran Year:2013 | Volume:32 | Issue:2 (68) Page(s): 1-13

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Title

STUDIES OF THE INTERACTION OF NI (II) COMPLEXES BEARING PLANAR AROMATIC LIGANDS WITH CALF THYMUS DNA

Author(s)

Keywords

NICKEL COMPLEXESQ2

INTERACTION WITH DNAQ2

INTERCALATIONQ2

Abstract

Three Nickel (II) complexes of formula [Ni (en)2] (N03)2 (a), [Ni (bpy)2](N03)2 (b) and [Ni (phen)2] (N03)2 (c) (where en=ethylenediamine, bpy=2,2 bipyridine and phen=1,10 phenanthroline) were prepared. The structure of these complexes have been characterized by spectroscopic methods such as infrared, ultraviolet visible and nuclear magnetic resonance and conductivity measurements and elemental analysis. Interaction of these three complexes with calf thymus DNA were carried out using ultraviolet- visible, fluorescence and jell- filterationtachniques. These complexes can denature the DNA at quite low concentrations. Complexes band c having aromatic surface presumably intercalate in DNA. Moreover complex c can cleave the DNA into two parts and interact with both.

Cites

SYNTHESIS, CHARACTERIZATION, ANTITUMOR PROPERTIES, DNA-INTERACTION AND EFFECT OF ELECTRICAL CHARGES PRESENT ON DIFFERENT RATIOS OF PD (II):ZN (II) COMPLEXES IN THEIR "COMBINATION THERAPY"

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APA: Copy

ESMAEILZAEI, ZOHREH, SABOURY, AIL AKBAR, MANSOURI TORSHIZI, HASAN, SAEIDIFAR, MARYAM, & DIVSALAR, ADELEH. (2013). STUDIES OF THE INTERACTION OF NI (II) COMPLEXES BEARING PLANAR AROMATIC LIGANDS WITH CALF THYMUS DNA. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), 32(2 (68)), 1-13. SID. https://sid.ir/paper/26178/en

Vancouver: Copy

ESMAEILZAEI ZOHREH, SABOURY AIL AKBAR, MANSOURI TORSHIZI HASAN, SAEIDIFAR MARYAM, DIVSALAR ADELEH. STUDIES OF THE INTERACTION OF NI (II) COMPLEXES BEARING PLANAR AROMATIC LIGANDS WITH CALF THYMUS DNA. NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN)[Internet]. 2013;32(2 (68)):1-13. Available from: https://sid.ir/paper/26178/en

IEEE: Copy

ZOHREH ESMAEILZAEI, AIL AKBAR SABOURY, HASAN MANSOURI TORSHIZI, MARYAM SAEIDIFAR, and ADELEH DIVSALAR, “STUDIES OF THE INTERACTION OF NI (II) COMPLEXES BEARING PLANAR AROMATIC LIGANDS WITH CALF THYMUS DNA,” NASHRIEH SHIMI VA MOHANDESI SHIMI IRAN (PERSIAN), vol. 32, no. 2 (68), pp. 1–13, 2013, [Online]. Available: https://sid.ir/paper/26178/en

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