PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT

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MOGHARNASI MEHDI; SHAHAMAT NASHTIFANI FARHAD; FOADODDINI MOHSEN; BANPARVARI MARYAM; BAYAT JAVAD; HOSSEINI MEHRAN

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Journal: JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT Year:2017 | Volume:4 | Issue:8 Page(s): 9-19

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Title

PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT

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Keywords

BOVINE COLOSTRUMQ1

EXERCISEQ2

LACTATE DEHYDROGENASEQ2

CREATINE KINASEQ2

RATQ2

Abstract

Background and Aim: Previous studies indicated that BOVINE COLOSTRUM (BC) has antioxidant activity, but the beneficial effects of BC on strenuous EXERCISE oxidative damage is remaining unclear. Thus, this study examined the effects of BC on EXERCISE induced muscle damage in RATs.Materials and Methods: Forty-eight male Wistar RATs randomly divided into 6 equal groups as: Group 1 (control), Group 2 (aerobic EXERCISE), Group 3 (anaerobic EXERCISE), Group 4 (supplements without EXERCISE), Group 5 (supplements with aerobic EXERCISE), Group 6 (supplements with anaerobic EXERCISE). After pretreating of BC, the blood sample from each group was taken in order to measure the levels of LACTATE DEHYDROGENASE (LDH) and CREATINE KINASE (CK). The data were analysed by ANOVA and Tukey test and significant level was set at p<0.05.Results: The plasma levels of LDH (P=0.010) and CK (P=0.006) significantly increased in anaerobic EXERCISE group in comparison with control group. There was no significant difference between aerobic EXERCISE group with the control (P=0.86). The mice were supplemented with EXERCISE and anaerobic EXERCISE extreme (Group 6) was significantly lower CK And LDH levels compared to anaerobic EXERCISE group without supplementation (group 3) had (P=0.001). The results revealed that BC pretreatment significantly prevented LDH and CK increasing induced by strenuous EXERCISE oxidative damage in RATs.Conclusion: colostrum supplement due to its antioxidant properties can be considered as a sports supplement and recommended to reduce muscle damage.

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APA: Copy

MOGHARNASI, MEHDI, SHAHAMAT NASHTIFANI, FARHAD, FOADODDINI, MOHSEN, BANPARVARI, MARYAM, BAYAT, JAVAD, & HOSSEINI, MEHRAN. (2017). PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT. JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT, 4(8), 9-19. SID. https://sid.ir/paper/262437/en

Vancouver: Copy

MOGHARNASI MEHDI, SHAHAMAT NASHTIFANI FARHAD, FOADODDINI MOHSEN, BANPARVARI MARYAM, BAYAT JAVAD, HOSSEINI MEHRAN. PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT. JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT[Internet]. 2017;4(8):9-19. Available from: https://sid.ir/paper/262437/en

IEEE: Copy

MEHDI MOGHARNASI, FARHAD SHAHAMAT NASHTIFANI, MOHSEN FOADODDINI, MARYAM BANPARVARI, JAVAD BAYAT, and MEHRAN HOSSEINI, “PROTECTIVE EFFECTS OF BOVINE COLOSTRUM SUPPLEMENTATION ON INDICATORS OF MUSCLE DAMAGE EXERCISE INDUCED IN RAT,” JOURNAL OF PRACTICAL STUDIES AT BIOSCIENCES IN SPORT, vol. 4, no. 8, pp. 9–19, 2017, [Online]. Available: https://sid.ir/paper/262437/en

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