COMBINED USE OF ERYTHROCYTE ZINC PROTOPORPHYRINE AND MCV: DIFFERENTIATION OF BETA THALASSEMIA FROM IRON DEFICIENCY ANEMIA

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KHOSHAMOOZ H.; HAJFATH ALI A.; POURFATH ELAH A.A.; KARIMI TEHRANI F.

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2001 | Volume:5 | Issue:4 Page(s): 341-346

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Title

COMBINED USE OF ERYTHROCYTE ZINC PROTOPORPHYRINE AND MCV: DIFFERENTIATION OF BETA THALASSEMIA FROM IRON DEFICIENCY ANEMIA

Author(s)

KHOSHAMOOZ H. | HAJFATH ALI A. | POURFATH ELAH A.A. | KARIMI TEHRANI F. | Issue Writer Certificate

Keywords

BETA THALASSEMIAQ3

IRON DEFICIENCY ANEMIAQ4

DIAGNOSTIC STUDYQ4

ZINC PROTOPORPHRYNQ3

Abstract

Introduction: Due to the prevalence of BETA THALASSEMIA and IRON DEFICIENCY ANEMIA in Irana need for an accurate, quick, inexpensive and simple method for differential diagnosis between these two disorders is felt. In this study the value of zpp measurement as a tool to distinguish iron deficiency from heterozygous BETA THALASSEMIA in microcrystal patients was evaluated.Methods: In this study on 140 persons with microcytosis, the hemoglobin electrophoresis, serum iron, TIBC and serum ferritin and protoporphyrine relating to zinc (ZPP) were measured.Results: ZPP had been increased in all iron deficient patients and in 53 percent of Heterozygote BETA THALASSEMIA patients. Using combination of MCV and ZPP in iron deficient anemic patients and heterozygote BETA THALASSEMIA show the 99 percent accuaracy in differentiation of these two disorders. Discussion: According to the results, this method has better accuracy than red blood cells formulation in the screening programs for BETA THALASSEMIA and iron defficiency anemia.

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APA: Copy

KHOSHAMOOZ, H., HAJFATH ALI, A., POURFATH ELAH, A.A., & KARIMI TEHRANI, F.. (2001). COMBINED USE OF ERYTHROCYTE ZINC PROTOPORPHYRINE AND MCV: DIFFERENTIATION OF BETA THALASSEMIA FROM IRON DEFICIENCY ANEMIA. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 5(4), 341-346. SID. https://sid.ir/paper/26557/en

Vancouver: Copy

KHOSHAMOOZ H., HAJFATH ALI A., POURFATH ELAH A.A., KARIMI TEHRANI F.. COMBINED USE OF ERYTHROCYTE ZINC PROTOPORPHYRINE AND MCV: DIFFERENTIATION OF BETA THALASSEMIA FROM IRON DEFICIENCY ANEMIA. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2001;5(4):341-346. Available from: https://sid.ir/paper/26557/en

IEEE: Copy

H. KHOSHAMOOZ, A. HAJFATH ALI, A.A. POURFATH ELAH, and F. KARIMI TEHRANI, “COMBINED USE OF ERYTHROCYTE ZINC PROTOPORPHYRINE AND MCV: DIFFERENTIATION OF BETA THALASSEMIA FROM IRON DEFICIENCY ANEMIA,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 5, no. 4, pp. 341–346, 2001, [Online]. Available: https://sid.ir/paper/26557/en

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