ANALGESIC AND ANTIINFLAMMATORY EFFECTS OF AMIRKABIRIA ODORATISSIMA

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HAJ HASHEMI V.A.; GHANNADI A.; SOLTANI L.

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2003 | Volume:7 | Issue:Supplement 2 Page(s): 121-125

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Title

ANALGESIC AND ANTIINFLAMMATORY EFFECTS OF AMIRKABIRIA ODORATISSIMA

Author(s)

HAJ HASHEMI V.A. | GHANNADI A. | SOLTANI L. | Issue Writer Certificate

Keywords

AMIRKABIRIA ODORATISSIMAQ4

ANALGESIC ACTIVITYQ4

ANTI-INFLAMMATORY ACTIVITYQ4

FLAVONOIDQ4

VOLATILE OILQ3

Abstract

Introduction. AMIRKABIRIA ODORATISSIMA, a plant of umbelliferae family grows in Isfahan and chaharmahal-Bakhtiary provinces. Traditionally, it has been used as analgesic and antiinflammatory but it has not been studied pharmacologically sofar. Therefore, this study was aimed to find pharmacological evidences to support this claim.Methods. Total extract, polyphenolic extract and VOLATILE OIL were prepared according to standard methods. Analgesia was assessed using acetic cicid-induced writhing, formalin test and light tail flick, Carrageenan test was used for evaluation of antiinflammatory effect.Results. In light tail flick, total and polyphenolic extracts (500mg/100g) had not analgesic effect while essence (0.25ml/100g) at 15 to 60 minutes showed analgesic effect. All three fractions could significantly (P<0.01) decrease the number of writhes in acetic acid test. In formalin test all fractions alleviate both phases of formalin pain. Results of carrageenan test showed that these fractions have antiinflammatory effect.Discussion. The examined fractions showed analgesic and antiinflammatory effects. The plant may lack analgesic compounds with opioid-like effect since none of the fractions had good analgesia in light tail flick test. Considering the results of writhing, formalin and carrageenan test, it seems that this plant may be more effective in controlling inflammatory pain.

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APA: Copy

HAJ HASHEMI, V.A., GHANNADI, A., & SOLTANI, L.. (2003). ANALGESIC AND ANTIINFLAMMATORY EFFECTS OF AMIRKABIRIA ODORATISSIMA. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 7(Supplement 2), 121-125. SID. https://sid.ir/paper/26688/en

Vancouver: Copy

HAJ HASHEMI V.A., GHANNADI A., SOLTANI L.. ANALGESIC AND ANTIINFLAMMATORY EFFECTS OF AMIRKABIRIA ODORATISSIMA. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2003;7(Supplement 2):121-125. Available from: https://sid.ir/paper/26688/en

IEEE: Copy

V.A. HAJ HASHEMI, A. GHANNADI, and L. SOLTANI, “ANALGESIC AND ANTIINFLAMMATORY EFFECTS OF AMIRKABIRIA ODORATISSIMA,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 7, no. Supplement 2, pp. 121–125, 2003, [Online]. Available: https://sid.ir/paper/26688/en

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