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Information Journal Paper

Title

SEXUAL DYSFUNCTION AND INFERTILITY: Optimal Number of Biopsies and Impact of Testicular Histology on the Outcome of Testicular Sperm Extraction

Pages

  795-801

Abstract

 PURPOSE: To determine the optimal number of biopsies in patients with non-obstructive azoospermia (NOA) who undergo testicular sperm extraction (TESE), and assess the impact of testicular histology on outcome. MATERIALS AND METHODS: Seven hundred and forty-one patients with NOA who underwent TESE in our institution were enrolled in the study. Testicular sperm extraction was performed applying an open surgical technique on the larger testis. The number of biopsies varied according to the presence or absence of spermatozoa. No further biopsies were obtained once spermatozoa were detected. If no spermatozoa were seen, the procedure was continued to a maximum number of 5 biopsies, including a single biopsy of the contralateral testis. RESULTS: Spermatozoa were obtained in 330 (44. 5%) patients after a single biopsy. The success rate increased to 381 (51. 4%), 416 (56. 1%), 433 (58. 4%), and 441 (59. 5%) after the second, third, fourth, and contralateral sampling, respectively. Multiple sampling increased the success rate; however, success rate did not increase considerably after the third sampling. Performing contralateral testicular biopsy was advantageous in patients with uniform or mixed pattern hypospermatogenesis. CONCLUSION: We recommend performing at least 3 biopsies in patients with NOA who undergo TESE. Further biopsies may also be advantageous when the NOA is a consequence of either uniform or mixed pattern hypospermatogenesis.

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    APA: Copy

    DADKHAH, FARID, HOSSEINI, SEYED JALIL, Sadighi Gilani, Mohamad Ali, FARRAHI, FARAMARZ, AMINI, ERFAN, & KAZEMINEJAD, BEHRANG. (2013). SEXUAL DYSFUNCTION AND INFERTILITY: Optimal Number of Biopsies and Impact of Testicular Histology on the Outcome of Testicular Sperm Extraction. UROLOGY JOURNAL, 10(1), 795-801. SID. https://sid.ir/paper/271077/en

    Vancouver: Copy

    DADKHAH FARID, HOSSEINI SEYED JALIL, Sadighi Gilani Mohamad Ali, FARRAHI FARAMARZ, AMINI ERFAN, KAZEMINEJAD BEHRANG. SEXUAL DYSFUNCTION AND INFERTILITY: Optimal Number of Biopsies and Impact of Testicular Histology on the Outcome of Testicular Sperm Extraction. UROLOGY JOURNAL[Internet]. 2013;10(1):795-801. Available from: https://sid.ir/paper/271077/en

    IEEE: Copy

    FARID DADKHAH, SEYED JALIL HOSSEINI, Mohamad Ali Sadighi Gilani, FARAMARZ FARRAHI, ERFAN AMINI, and BEHRANG KAZEMINEJAD, “SEXUAL DYSFUNCTION AND INFERTILITY: Optimal Number of Biopsies and Impact of Testicular Histology on the Outcome of Testicular Sperm Extraction,” UROLOGY JOURNAL, vol. 10, no. 1, pp. 795–801, 2013, [Online]. Available: https://sid.ir/paper/271077/en

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