EVALUATION OF TOPICAL TRANEXAMIC ACID ON INTRAOPERATIVE BLEEDING IN ENDOSCOPE SINUS SURGERY

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JAB ALAMELI M.; ZAKERI K.

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Journal Paper

Paper Information

Journal: Iranian Journal of Medical Sciences Year:2006 | Volume:31 | Issue:4 Page(s): 221-223

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Information Journal Paper

Title

EVALUATION OF TOPICAL TRANEXAMIC ACID ON INTRAOPERATIVE BLEEDING IN ENDOSCOPE SINUS SURGERY

Author(s)

JAB ALAMELI M. | ZAKERI K. | Issue Writer Certificate

Keywords

TRANEXAMIC ACID

BLEEDING

ENDOSCOPIC SINUS SURGERY

Abstract

TRANEXAMIC ACID (TA) is an antifibrinolytic agent which reduces BLEEDING following certain surgical procedures. The present study was performed on 56 patients, scheduled for elective ENDOSCOPIC SINUS SURGERY under general anesthesia, to examine the effects of topical TA on providing a bloodless surgical field and evaluate the BLEEDING volume. The study comprised 26 patients who received topical TA and 30 patients used placebo. The homodynamic endpoints were to maintain the mean arterial blood pressure at 30% bellow its preoperative level. Intraoperative BLEEDING was assessed using a six point scale. There was less BLEEDING volume in the TA group than in the placebo group (174.0±10.6 vs 229.1±23.8 ml; P<0.05). The frequency of score 3 was 26% in TA group which was significantly lower than of placebo group (70%).The BLEEDING score of TA group was significantly lower than of placebo group (2.3±0.2 vs. 2.5±0.15). In conclusion it seems that topical application of TRANEXAMIC ACID reduces intraoperative BLEEDING in ENDOSCOPIC SINUS SURGERY.

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APA: Copy

JAB ALAMELI, M., & ZAKERI, K.. (2006). EVALUATION OF TOPICAL TRANEXAMIC ACID ON INTRAOPERATIVE BLEEDING IN ENDOSCOPE SINUS SURGERY. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), 31(4), 221-223. SID. https://sid.ir/paper/276060/en

Vancouver: Copy

JAB ALAMELI M., ZAKERI K.. EVALUATION OF TOPICAL TRANEXAMIC ACID ON INTRAOPERATIVE BLEEDING IN ENDOSCOPE SINUS SURGERY. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)[Internet]. 2006;31(4):221-223. Available from: https://sid.ir/paper/276060/en

IEEE: Copy

M. JAB ALAMELI, and K. ZAKERI, “EVALUATION OF TOPICAL TRANEXAMIC ACID ON INTRAOPERATIVE BLEEDING IN ENDOSCOPE SINUS SURGERY,” IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), vol. 31, no. 4, pp. 221–223, 2006, [Online]. Available: https://sid.ir/paper/276060/en

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