EVALUATION OF SERUM LEVELS OF IL-1α, TGF-β, TNF-α, IFN-α, IFN-Y, CORTISOL AND IMMUNOGLOBULINS IN ISLAMIC RAMADAN FASTING

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SHARIFI F.A.S.; MASOUD A.; REZAEI MAKAN; ZIAEI M.; HEDAYATI S.M.

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Journal: Iranian Journal of Endocrinology & Metabolism Year:2007 | Volume:9 | Issue:2 (SN 34) Page(s): 201-204

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Title

EVALUATION OF SERUM LEVELS OF IL-1α, TGF-β, TNF-α, IFN-α, IFN-Y, CORTISOL AND IMMUNOGLOBULINS IN ISLAMIC RAMADAN FASTING

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ISLAMIC RAMADAN FASTINGQ3

CYTOKINEQ2

CORTISOLQ2

IMMUNOGLOBULINEQ2

Abstract

Introduction: This research aimed determining the levels of CORTISOL, immunoglobulins and major serum CYTOKINEs, following Ramadan fasting, as immune response indexes. Materials and Methods: For this before and after Ramadan fasting study, twenty-five students residing at the dormitory of the Tehran University of Medical Sciences were selected. All CYTOKINEs levels (IL-1a, TGF-b, TNF- a, IFN-a, IFN-g) were determined by the ELISA method, Immoglobulines were determined by the Radial Immunodiffusion (SRID) technique and CORTISOL levels were measured by EIA too. Results: While IFN-g a showed a considerable increase after Ramadan fasting (P<0.01), IFN-a and TNF-a had decreased (P≥0.5 and <0.02 respectively). Serum level of TGF-b increased but not significantly (P>0.3); CORTISOL also increased after one month of fasting (P<0.05). Serum IL-1α had a non-significant decrease (P≥0.5). Although IgG & IgM levels showed no significant increase, IgA levels showed significant decrease [P<0.5].Conclusion: Our data revealed that Ramadan fasting increased IFN-g, while decreasing TNF-a and IgA levels; ramadan fasting can probably increase T-Cell function, lower the inflammatory appreance rate and affect immunoglobulin production.

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APA: Copy

SHARIFI, F.A.S., MASOUD, A., REZAEI, MAKAN, ZIAEI, M., & HEDAYATI, S.M.. (2007). EVALUATION OF SERUM LEVELS OF IL-1α, TGF-β, TNF-α, IFN-α, IFN-Y, CORTISOL AND IMMUNOGLOBULINS IN ISLAMIC RAMADAN FASTING. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 9(2 (SN 34)), 201-204. SID. https://sid.ir/paper/27678/en

Vancouver: Copy

SHARIFI F.A.S., MASOUD A., REZAEI MAKAN, ZIAEI M., HEDAYATI S.M.. EVALUATION OF SERUM LEVELS OF IL-1α, TGF-β, TNF-α, IFN-α, IFN-Y, CORTISOL AND IMMUNOGLOBULINS IN ISLAMIC RAMADAN FASTING. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2007;9(2 (SN 34)):201-204. Available from: https://sid.ir/paper/27678/en

IEEE: Copy

F.A.S. SHARIFI, A. MASOUD, MAKAN REZAEI, M. ZIAEI, and S.M. HEDAYATI, “EVALUATION OF SERUM LEVELS OF IL-1α, TGF-β, TNF-α, IFN-α, IFN-Y, CORTISOL AND IMMUNOGLOBULINS IN ISLAMIC RAMADAN FASTING,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 9, no. 2 (SN 34), pp. 201–204, 2007, [Online]. Available: https://sid.ir/paper/27678/en

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