PREVALENCE OF INHIBITORS IN A POPULATION OF 1280 HEMOPHILIA A PATIENTS IN IRAN

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SHARIFIAN H.; HOSEINI M.; SAFAI R.; TUGEH GH.; EHSANI A.H.; LAK M.; JAZEBI M.

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Journal Paper

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Journal: ACTA MEDICA IRANICA Year:2003 | Volume:41 | Issue:1 Page(s): 66-68

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Title

PREVALENCE OF INHIBITORS IN A POPULATION OF 1280 HEMOPHILIA A PATIENTS IN IRAN

Author(s)

Keywords

HEMOPHILIA A

INHIBITORS

PREVALENCE

FACTOR VIII

Abstract

Development of inhibitor to FACTOR VIII is the most serious complication of hemophilia therapy. To determine the PREVALENCE of INHIBITORS in Iran HEMOPHILIA A patients exposed to blood products, 1280 HEMOPHILIA A patients (age range 9 months-84 years) were evaluated. All patients received several blood products such as fresh frozen plasma (FFP), cryoprecipitate, FACTOR VIII. 635 of 1280 patients (49.6%), 277 patients (21.6%) and 368 patients (28.8%) had sever, moderate and mild disease, respectively. 184 of 1280 patients (14.4%) developed inhibitor. The PREVALENCE of inhibitor for severe, moderate and mild in HEMOPHILIA A patients was 22.8%, 9.4%, 3.5% respectively. 41 patients (22.2%) and 1, patients (77.8%) were high responder and low responder respectively. Among 184 patients with inhibitor, 67 patients (36.4%) had blood group O and for B, A, AB blood groups, number of patients with inhibitor was 55 (29.9%), 50 (27.2%) 12 (6.5%) respectively and 153 patients (83.1%) had Rh blood group.

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APA: Copy

SHARIFIAN, H., HOSEINI, M., SAFAI, R., TUGEH, GH., EHSANI, A.H., LAK, M., & JAZEBI, M.. (2003). PREVALENCE OF INHIBITORS IN A POPULATION OF 1280 HEMOPHILIA A PATIENTS IN IRAN. ACTA MEDICA IRANICA, 41(1), 66-68. SID. https://sid.ir/paper/277511/en

Vancouver: Copy

SHARIFIAN H., HOSEINI M., SAFAI R., TUGEH GH., EHSANI A.H., LAK M., JAZEBI M.. PREVALENCE OF INHIBITORS IN A POPULATION OF 1280 HEMOPHILIA A PATIENTS IN IRAN. ACTA MEDICA IRANICA[Internet]. 2003;41(1):66-68. Available from: https://sid.ir/paper/277511/en

IEEE: Copy

H. SHARIFIAN, M. HOSEINI, R. SAFAI, GH. TUGEH, A.H. EHSANI, M. LAK, and M. JAZEBI, “PREVALENCE OF INHIBITORS IN A POPULATION OF 1280 HEMOPHILIA A PATIENTS IN IRAN,” ACTA MEDICA IRANICA, vol. 41, no. 1, pp. 66–68, 2003, [Online]. Available: https://sid.ir/paper/277511/en

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