COMPARISON OF RADIOIODINE AND ANTITHYROID DRUGS IN THE TREATMENT OF THYROTOXICOSIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HEYDARI- B.; FARHANGI F.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2002 | Volume:4 | Issue:1(SN 13) Page(s): 29-34

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,737

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF RADIOIODINE AND ANTITHYROID DRUGS IN THE TREATMENT OF THYROTOXICOSIS

Author(s)

HEYDARI- B. | FARHANGI F. | Issue Writer Certificate

Keywords

THYROTOXICOSISQ3

RADIOIODINEQ3

ANTITHYROID DRUGSQ4

EUTHYROIDISMQ4

Abstract

Introduction: None of the current available long-term therapies for THYROTOXICOSIS is ideal, and the choice for each patient must be made individually. The purpose of the present study is to compare the two choices of treatment, the RADIOIODINE and antithyroid drug therapy. Materials and Methods: The study population were thyrotoxic patients treated in Shaheed Beheshti Hospital of Babol between April 1997 to May 2000. Diagnosis of THYROTOXICOSIS was based on the clinical features and assessment of serum TSH, T4 and T3 levels. Patients with thyroiditis and patients non compliant to regular treatment were excluded. Standard antithyroid drug therapy was started for all patients and continued until the occurence of remission, then tapered off and discontinued. Patients unresponsive to at least six months of drug therapy or patients with disease recurrence after, at least, a three month remission period, were treated with 8-15 mci, of RADIOIODINE and continuation of antithyroid therapy until reaching a euthyroid state. All patients were followed during the treatment period and for at least one year after the beginning of remission. Results: 30 patients (20 females, 10 males) with a mean age of 46±11 years and 44 patients (22 females, 22 males) with a mean age of 37±14 were treated by RADIOIODINE and ANTITHYROID DRUGS. The disease duration in the two age groups was 14±33 and 10.5±15 months respectively (p=NS), and causes of THYROTOXICOSIS in the two groups were: Graves’ disease in 63% and 79.5%, toxic multinodular goiter in 27% and 11.5% (p<0.05), toxic nodular goiter in 10 and 9% of patients. After a mean follow-up of 19.7±21 months, 60% of patients achieved remission by radiodine and 40% became hypothyroid, whereas 45% of patients achieved remission by ANTITHYROID DRUGS and 55% remained hyperthyroid for as long as 28±19 months. The duration of antithyroid drug therapy in each group was 3.3±4.8 and 13.3±8.3 months, respectively. No drug reaction or recurrence was observed during the remission period of 17.5±19 and 21±18 months. Conclusion: On a short term basis, the outcome of THYROTOXICOSIS for remission is similar either by RADIOIODINE or antithyroid drug therapy, but development of hypothyroidism in the former and persistance of hyperthyroid state in the latter, gives RADIOIODINE therapy priority.

Cites

No record.

References

No record.

Cite

APA: Copy

HEYDARI-, B., & FARHANGI, F.. (2002). COMPARISON OF RADIOIODINE AND ANTITHYROID DRUGS IN THE TREATMENT OF THYROTOXICOSIS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 4(1(SN 13)), 29-34. SID. https://sid.ir/paper/27761/en

Vancouver: Copy

HEYDARI- B., FARHANGI F.. COMPARISON OF RADIOIODINE AND ANTITHYROID DRUGS IN THE TREATMENT OF THYROTOXICOSIS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2002;4(1(SN 13)):29-34. Available from: https://sid.ir/paper/27761/en

IEEE: Copy

B. HEYDARI-, and F. FARHANGI, “COMPARISON OF RADIOIODINE AND ANTITHYROID DRUGS IN THE TREATMENT OF THYROTOXICOSIS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 4, no. 1(SN 13), pp. 29–34, 2002, [Online]. Available: https://sid.ir/paper/27761/en

Related Journal Papers