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Information Journal Paper

Title

COMPARISON OF DINOPROSTONE PLUS ‎OXYTOCIN AND OXYTOCIN ALONE FOR INDUCTION ‎OF LABOR

Pages

  259-262

Abstract

 Role of LABOR INDUCTION has increased in the last decade due to the ‎early detection of fetal jeopardy. Although very useful, OXYTOCIN alone is not always successful for INDUCTION of ‎labor. In a randomized clinical ‎trial we compared vaginal DINOPROSTONE plus OXYTOCIN with OXYTOCIN alone for ‎INDUCTION of LABOR in 91 ‎pregnant women at 40 weeks or greater gestation with Bishop scores ≤ 4. Forty six patients ‎assigned to the DINOPROSTONE group received 3 mg intravaginal dinoprostone. Six ‎hours later the Bishop score was evaluated and if the patient had not at least 3 contractions in ‎10 minutes lasting for more than 40 seconds, intravenous OXYTOCIN was started at a dose of 6 mu/min and ‎increased by 6 mu/min at 40 minute intervals until adequate uterine activity. Forty five patients ‎assigned to the OXYTOCIN group underwent OXYTOCIN INDUCTION from the start of LABOR induction. ‎Although the Bishop score change after 6 hours of receiving vaginal DINOPROSTONE from 2.54 ‎to 4.97 was statistically significant, the OXYTOCIN only group had a much better response with a change from ‎2.60 to 6.28. Median time between INDUCTION to the start of active LABOR was significantly ‎shorter in the OXYTOCIN alone group (P = 0.04). Median time between ‎INDUCTION to delivery and the rate of cesarean did not differ significantly in two groups (P > ‎0.05). It was concluded that single dose of ‎dinoprostone is effective for initiating LABOR in patients with an unfavorable cervix and ‎appears safe but it is not as effective as oxytocin.

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    Cite

    APA: Copy

    VALADAN, M., KHALILIAN, S., NIROUMANESH, S., TEHRANI, M., & NOORI, K.. (2005). COMPARISON OF DINOPROSTONE PLUS ‎OXYTOCIN AND OXYTOCIN ALONE FOR INDUCTION ‎OF LABOR. ACTA MEDICA IRANICA, 43(4), 259-262. SID. https://sid.ir/paper/277859/en

    Vancouver: Copy

    VALADAN M., KHALILIAN S., NIROUMANESH S., TEHRANI M., NOORI K.. COMPARISON OF DINOPROSTONE PLUS ‎OXYTOCIN AND OXYTOCIN ALONE FOR INDUCTION ‎OF LABOR. ACTA MEDICA IRANICA[Internet]. 2005;43(4):259-262. Available from: https://sid.ir/paper/277859/en

    IEEE: Copy

    M. VALADAN, S. KHALILIAN, S. NIROUMANESH, M. TEHRANI, and K. NOORI, “COMPARISON OF DINOPROSTONE PLUS ‎OXYTOCIN AND OXYTOCIN ALONE FOR INDUCTION ‎OF LABOR,” ACTA MEDICA IRANICA, vol. 43, no. 4, pp. 259–262, 2005, [Online]. Available: https://sid.ir/paper/277859/en

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