COMPARISON OF FUMARIC ACID 5% CREAM VERSUS TRIAMCINOLONE 0.1% CREAM IN THE TREATMENT OF HAND ECZEMA

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JOWKAR FARIDEH; SAKI NASRIN; MOKHTARPOUR AKBAR; SAKI MOHAMMAD REZA

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Journal Paper

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Journal: ACTA MEDICA IRANICA Year:2014 | Volume:52 | Issue:7 Page(s): 528-531

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Information Journal Paper

Title

COMPARISON OF FUMARIC ACID 5% CREAM VERSUS TRIAMCINOLONE 0.1% CREAM IN THE TREATMENT OF HAND ECZEMA

Author(s)

JOWKAR FARIDEH | SAKI NASRIN | MOKHTARPOUR AKBAR | SAKI MOHAMMAD REZA | Issue Writer Certificate

Keywords

HAND ECZEMA

FUMARIC ACID

TRIAMCINOLONE

IMMUNE SYSTEM

Abstract

HAND ECZEMA is a common distressing skin problem. It is an immune reaction to haptens. Thus, substances that inhibit IMMUNE SYSTEM can be effective in the treatment of HAND ECZEMA. In this study, topical FUMARIC ACID 5% cream is compared with topical steroid in the treatment of HAND ECZEMA. Patients with HAND ECZEMA were randomly divided into two groups. One group received FUMARIC ACID 5% in a cream base, and the other received TRIAMCINOLONE 0.1% in the same cream base. Both groups used creams twice daily for one month. Patients were checked for erythema, excoriation, population and lichenification, EASI score, and pruritus before and after treatment. In both groups, the mean of all signs of the disease and EASI score decreased after one month of treatment. There was no significant difference between the two treatments in decreasing erythema, but excoriation, population, lichenification, EASI score and itching were all decreased more in TRIAMCINOLONE 0.1 % group. Although FUMARIC ACID can inhibit the IMMUNE SYSTEM; it was less effective for the treatment of all signs of HAND ECZEMA except erythema in comparison to TRIAMCINOLONE. These results may be justified for two reasons: low penetration of topical FUMARIC ACID through the skin or a low concentration used in this study.

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APA: Copy

JOWKAR, FARIDEH, SAKI, NASRIN, MOKHTARPOUR, AKBAR, & SAKI, MOHAMMAD REZA. (2014). COMPARISON OF FUMARIC ACID 5% CREAM VERSUS TRIAMCINOLONE 0.1% CREAM IN THE TREATMENT OF HAND ECZEMA. ACTA MEDICA IRANICA, 52(7), 528-531. SID. https://sid.ir/paper/278609/en

Vancouver: Copy

JOWKAR FARIDEH, SAKI NASRIN, MOKHTARPOUR AKBAR, SAKI MOHAMMAD REZA. COMPARISON OF FUMARIC ACID 5% CREAM VERSUS TRIAMCINOLONE 0.1% CREAM IN THE TREATMENT OF HAND ECZEMA. ACTA MEDICA IRANICA[Internet]. 2014;52(7):528-531. Available from: https://sid.ir/paper/278609/en

IEEE: Copy

FARIDEH JOWKAR, NASRIN SAKI, AKBAR MOKHTARPOUR, and MOHAMMAD REZA SAKI, “COMPARISON OF FUMARIC ACID 5% CREAM VERSUS TRIAMCINOLONE 0.1% CREAM IN THE TREATMENT OF HAND ECZEMA,” ACTA MEDICA IRANICA, vol. 52, no. 7, pp. 528–531, 2014, [Online]. Available: https://sid.ir/paper/278609/en

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