مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

914
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EFFECTS OF ORAL CRATAEGUS SPP BRANCHLET ON SERUM CONCENTRATION OF GLUCOSE AND LIPID AND PROTECTION OF BETA CELLS IN DIABETIC RATS

Pages

  323-329

Abstract

 Introduction: Medicinal plants are known for their effects in attenuation of hyperglycemia and restoration of LIPIDs to normal levels. In this study, the effects of oral administration of CRATAEGUS SPP (CS) branchlet on serum GLUCOSE, LIPIDs, and BETA CELL density in diabetic rats were investigated. Materials and Methods: Male NMRI rats (n = 32) were divided into 4 groups, i.e. control, CS-treated control, diabetic, and the CS-treated diabetic groups. The treatment groups received oral administration of plant-mixed pelleted food (6.25%) for 6 weeks. Serum GLUCOSE, triglycerides, total cholesterol, LDL- and HDL- cholesterol concentrations were determined before the study, and 3 and 6 weeks after the study. Density of BETA CELLs in in 4 groups was determined using the monochrome Gomori staining method. Results: Serum GLUCOSE concentration was significantly lower in the CS-treated diabetic group, compared to diabetics, 3 and 6 weeks after the study (p<0.05). In addition, there were no significant changes regarding serum total cholesterol, triglycerides, and HDL-cholesterol concentrations in the treated diabetic group as compared to the diabetic group. On the other hand, the treated diabetic group showed significantly lower levels of LDL-cholesterol as compared to the diabetic group (p<0.05). Regarding histology, BETA CELL density significantly decreased in diabetic rats, while CS treatment caused no changes. Conclusion: Oral administration of CS has a significant hypoglycemic effect and lowers serum LDL-cholesterol.

Cites

  • No record.
  • References

  • No record.
  • Cite

    APA: Copy

    SEDAGHAT, R., ROGHANI, MEHRDAD, & ZAREEI, MOHSEN. (2009). EFFECTS OF ORAL CRATAEGUS SPP BRANCHLET ON SERUM CONCENTRATION OF GLUCOSE AND LIPID AND PROTECTION OF BETA CELLS IN DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 11(3 (SN 45)), 323-329. SID. https://sid.ir/paper/27882/en

    Vancouver: Copy

    SEDAGHAT R., ROGHANI MEHRDAD, ZAREEI MOHSEN. EFFECTS OF ORAL CRATAEGUS SPP BRANCHLET ON SERUM CONCENTRATION OF GLUCOSE AND LIPID AND PROTECTION OF BETA CELLS IN DIABETIC RATS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2009;11(3 (SN 45)):323-329. Available from: https://sid.ir/paper/27882/en

    IEEE: Copy

    R. SEDAGHAT, MEHRDAD ROGHANI, and MOHSEN ZAREEI, “EFFECTS OF ORAL CRATAEGUS SPP BRANCHLET ON SERUM CONCENTRATION OF GLUCOSE AND LIPID AND PROTECTION OF BETA CELLS IN DIABETIC RATS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 11, no. 3 (SN 45), pp. 323–329, 2009, [Online]. Available: https://sid.ir/paper/27882/en

    Related Journal Papers

    Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button