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Title

VIRULENCE GENES PROFILE OF MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM IRANIAN CHILDREN WITH UTIS

Pages

  201-210

Abstract

 Virulent and resistant strainsPSEUDOMONAS AERUGINOSA (P. aeruginosa) is one of the most important cause of UTIs in PEDIATRICS. The present study was carried to investigate the frequency of VIRULENCE FACTORS in the multi-drug resistant strains ofP. aeruginosa isolated from PEDIATRICS hospitalized due to the UTIs. One - hundred and forty three urine samples were collected from pediatric patients suffered from UTIs.Samples were cultured and those that wereP. aeruginosa positive were analyzed for the presence of putative virulence genes. Seventy one out of 143 samples (49.65%) were positive for P. aeruginosa. Monthly, sex and age-dependent prevalence were seen for P. aeruginosa. Bacterial strains had the highest levels of resistance against ampicillin (95.77%), gentamicin (92.95%) and ciprofloxacin (81.69%). Of 71P. aeruginosa isolates, 12 strains were resistant to more than 9 antibiotics (16.90%). The most commonly detected VIRULENCE FACTORS in the cases of urethral infections were exoU and plcH while those of pyelonephritis and cystitis were were exoS and lasB. Our findings should raise awareness about antibiotic resistance in hospitalized PEDIATRICS with UTIs in Iran. Clinicians should exercise caution in prescribing antibiotics, especially in cases of UTIs. Such information can help in identifying these virulence genes as useful diagnostic markers for clinicalP.aeruginosastrains isolated from UTIs.

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    APA: Copy

    HEIDARY, ZOHREH, BANDANI, ESHAGH, EFTEKHARY, MOHAMAD, & JAFARI, ALI AKBAR. (2016). VIRULENCE GENES PROFILE OF MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM IRANIAN CHILDREN WITH UTIS. ACTA MEDICA IRANICA, 54(3), 201-210. SID. https://sid.ir/paper/278892/en

    Vancouver: Copy

    HEIDARY ZOHREH, BANDANI ESHAGH, EFTEKHARY MOHAMAD, JAFARI ALI AKBAR. VIRULENCE GENES PROFILE OF MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM IRANIAN CHILDREN WITH UTIS. ACTA MEDICA IRANICA[Internet]. 2016;54(3):201-210. Available from: https://sid.ir/paper/278892/en

    IEEE: Copy

    ZOHREH HEIDARY, ESHAGH BANDANI, MOHAMAD EFTEKHARY, and ALI AKBAR JAFARI, “VIRULENCE GENES PROFILE OF MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM IRANIAN CHILDREN WITH UTIS,” ACTA MEDICA IRANICA, vol. 54, no. 3, pp. 201–210, 2016, [Online]. Available: https://sid.ir/paper/278892/en

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