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Title

CLINICAL AND HISTOLOGICAL PRESENTATION OF HELICOBACTER PYLORI AND GLUTEN RELATED GASTROENTEROPATHY

Pages

  115-119

Abstract

 Background: CELIAC DISEASE has been reported to be associated with gastric abnormalities. The aim of this study was to assess the relationship between the prevalence of CELIAC DISEASE and HELICOBACTER PYLORI infection in an Iranian population of 250 patients.Methods: Biopsies were taken from the gastric antrum and duodenum. Morphology and histology were evaluated using the updated Sydney system and modied Marsh criteria, respectively. To simplify the interpretation of gastric lesions we classied gastritis in macroscopic and microscopic stages. Serology for anti-tissue transglutaminase antibody was performed to determine the presence of CELIAC DISEASE.Results: Among 250 patients, 232 (93%) had histological evidence of HELICOBACTER PYLORI infection. Histological abnormalities (Marsh I to IIIc) were present in 24 (10%) . Of 24 patients, 20 (83%) with histological abnormalities were infected with HELICOBACTER PYLORI. Of 250 patients, 25 (10%) had a positive anti-tissue transglutaminase antibody. Of 25 anti-tissue transglutaminase antibody positive patients, 9 (3.6%) had microscopic and macroscopic enteritis (Marsh I to IIIc) .Conclusions: Clinical presentation of CELIAC DISEASE was not distinguishable from cases infected with HELICOBACTER PYLORI. Histology, even in patients with positive serology, was non-specic and unhelpful. We found a high prevalence of HELICOBACTER PYLORI infection and chronic gastritis, but neither was associated with CELIAC DISEASE, in agreement with studies in Western populations.

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    APA: Copy

    ROSTAMI NEJAD, MOHAMMAD, ROSTAMI, KAMRAN, YAMAOKA, YOSHIO, MASHAYEKHI, REZA, MOLAEI, MAHSA, DABIRI, HOSSEIN, AL DULAIMI, DAVID, MIRSATTARI, DARIUSH, ZOJAJI, HOMAYOUN, NOROUZINIA, MOHSEN, & ZALI, MOHAMMAD REZA. (2011). CLINICAL AND HISTOLOGICAL PRESENTATION OF HELICOBACTER PYLORI AND GLUTEN RELATED GASTROENTEROPATHY. ARCHIVES OF IRANIAN MEDICINE, 14(2), 115-119. SID. https://sid.ir/paper/280647/en

    Vancouver: Copy

    ROSTAMI NEJAD MOHAMMAD, ROSTAMI KAMRAN, YAMAOKA YOSHIO, MASHAYEKHI REZA, MOLAEI MAHSA, DABIRI HOSSEIN, AL DULAIMI DAVID, MIRSATTARI DARIUSH, ZOJAJI HOMAYOUN, NOROUZINIA MOHSEN, ZALI MOHAMMAD REZA. CLINICAL AND HISTOLOGICAL PRESENTATION OF HELICOBACTER PYLORI AND GLUTEN RELATED GASTROENTEROPATHY. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2011;14(2):115-119. Available from: https://sid.ir/paper/280647/en

    IEEE: Copy

    MOHAMMAD ROSTAMI NEJAD, KAMRAN ROSTAMI, YOSHIO YAMAOKA, REZA MASHAYEKHI, MAHSA MOLAEI, HOSSEIN DABIRI, DAVID AL DULAIMI, DARIUSH MIRSATTARI, HOMAYOUN ZOJAJI, MOHSEN NOROUZINIA, and MOHAMMAD REZA ZALI, “CLINICAL AND HISTOLOGICAL PRESENTATION OF HELICOBACTER PYLORI AND GLUTEN RELATED GASTROENTEROPATHY,” ARCHIVES OF IRANIAN MEDICINE, vol. 14, no. 2, pp. 115–119, 2011, [Online]. Available: https://sid.ir/paper/280647/en

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