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Information Journal Paper

Title

UNSUSPECTED GALLBLADDER CANCER: A CLINICAL RETROSPECTIVE STUDY

Pages

  631-635

Abstract

 BACKGROUND: The morbidity of UNSUSPECTED GALLBLADDER CARCINOMA (UGC) has increased. This study was aimed to explore the factors which may influence the therapeutic strategies and prognosis of UCG. Additionally, long-term prognosis of laparoscopic and open surgeries of UGC was comparatively investigated.METHODS: Thirty-eight cases of UGC were enrolled in this study. Statistical analysis of survival was performed using the Kaplan–Meier test and the results were examined using the log-rank test.RESULTS: The morbidity of UGC was 0.43%. The cancer stagings were: pT1a (one), pT1b (11), pT2 (14), pT3 (10), pT3N1 (one), and pT4 (one). The median lifespan of the entire cohort was 20.0±6.5 months, one-year survival rate was 44%, and five-year survival rate was 11 %. One-year recurrence- free survival rate was 44% and three-year recurrence- free survival rate was 0 %. Twenty-eight patients sustained cancer recurrence and three patients sustained port-site cancer recurrence. The cancer staging (P<0.01) and radical resection (P<0.01) were independent factors for both overall and recurrence-free survival. Radical resection improved the prognosis of the patients with pT2 stage UGC (P<0.05), but no significant impact on the prognosis of the patients with pT1b (P=0.362) or pT3 stage (P=0.221) UGC. Survival rates were not significantly affected by the first operation no matter it was laparoscopic surgery or open surgery (P=0.12).CONCLUSION: Radical resection surgery is recommended in pT2 stage UGC. There is no difference for the long-term prognosis between laparoscopic surgery (cholecystectomy) and open surgery of UCG.

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  • Cite

    APA: Copy

    HU, LIANGSHUO, BO, WANG, LIU, XUEMIN, & LV, YI. (2013). UNSUSPECTED GALLBLADDER CANCER: A CLINICAL RETROSPECTIVE STUDY. ARCHIVES OF IRANIAN MEDICINE, 16(11), 631-635. SID. https://sid.ir/paper/281103/en

    Vancouver: Copy

    HU LIANGSHUO, BO WANG, LIU XUEMIN, LV YI. UNSUSPECTED GALLBLADDER CANCER: A CLINICAL RETROSPECTIVE STUDY. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2013;16(11):631-635. Available from: https://sid.ir/paper/281103/en

    IEEE: Copy

    LIANGSHUO HU, WANG BO, XUEMIN LIU, and YI LV, “UNSUSPECTED GALLBLADDER CANCER: A CLINICAL RETROSPECTIVE STUDY,” ARCHIVES OF IRANIAN MEDICINE, vol. 16, no. 11, pp. 631–635, 2013, [Online]. Available: https://sid.ir/paper/281103/en

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