PRIMARY NONSECRETORY PLASMA CELL LEUKEMIA WITH MULTIPLE CHROMOSOMAL ABNORMALITIES: A CASE REPORT

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NAKAYAMA SATOSHI; ODA TOMOHIRO; MINABE SHINYA; BAMBA YUKIHARU; UKAWA HARUKO; SATO RIKA; KAWABATA MASAKI; HORIUCHI TOSHIKATSU; WATANABE JUNICHI; KIMURA FUMIHIKO; SHIMAZAKI HIDEYUKI; OGATA SHO; NAKANISHI KUNIAKI

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Journal: ARCHIVES OF IRANIAN MEDICINE Year:2018 | Volume:21 | Issue:1 Page(s): 41-43

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Title

PRIMARY NONSECRETORY PLASMA CELL LEUKEMIA WITH MULTIPLE CHROMOSOMAL ABNORMALITIES: A CASE REPORT

Author(s)

Keywords

MULTIPLE MYELOMA

NONSECRETORY TYPE

PLASMA CELL LEUKEMIA

Abstract

Primary nonsecretory PLASMA CELL LEUKEMIA (PCL) is an extremely rare type of MULTIPLE MYELOMA. Here, we report a case of nonsecretory PCL with no previous history of MULTIPLE MYELOMA. The case exhibited extremely low levels of serum immunoglobulin and light chain, no detectable serum M-protein or free light chain restriction, no urine BJP, and no cytoplasmic light chain expression in flow cytometry. In fluorescence in situ hybridization, tumor cells exhibited fusion genes for IgH/BCL1 and IgH/c-Myc, disappearance of the p53 signal, and a split signal for IgK(2p11), but no split signal for IgL (22q11). Therefore, we diagnosed primary nonsecretory PCL with multiple chromosomal abnormalities.

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APA: Copy

NAKAYAMA, SATOSHI, ODA, TOMOHIRO, MINABE, SHINYA, BAMBA, YUKIHARU, UKAWA, HARUKO, SATO, RIKA, KAWABATA, MASAKI, HORIUCHI, TOSHIKATSU, WATANABE, JUNICHI, KIMURA, FUMIHIKO, SHIMAZAKI, HIDEYUKI, OGATA, SHO, & NAKANISHI, KUNIAKI. (2018). PRIMARY NONSECRETORY PLASMA CELL LEUKEMIA WITH MULTIPLE CHROMOSOMAL ABNORMALITIES: A CASE REPORT. ARCHIVES OF IRANIAN MEDICINE, 21(1), 41-43. SID. https://sid.ir/paper/281589/en

Vancouver: Copy

NAKAYAMA SATOSHI, ODA TOMOHIRO, MINABE SHINYA, BAMBA YUKIHARU, UKAWA HARUKO, SATO RIKA, KAWABATA MASAKI, HORIUCHI TOSHIKATSU, WATANABE JUNICHI, KIMURA FUMIHIKO, SHIMAZAKI HIDEYUKI, OGATA SHO, NAKANISHI KUNIAKI. PRIMARY NONSECRETORY PLASMA CELL LEUKEMIA WITH MULTIPLE CHROMOSOMAL ABNORMALITIES: A CASE REPORT. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2018;21(1):41-43. Available from: https://sid.ir/paper/281589/en

IEEE: Copy

SATOSHI NAKAYAMA, TOMOHIRO ODA, SHINYA MINABE, YUKIHARU BAMBA, HARUKO UKAWA, RIKA SATO, MASAKI KAWABATA, TOSHIKATSU HORIUCHI, JUNICHI WATANABE, FUMIHIKO KIMURA, HIDEYUKI SHIMAZAKI, SHO OGATA, and KUNIAKI NAKANISHI, “PRIMARY NONSECRETORY PLASMA CELL LEUKEMIA WITH MULTIPLE CHROMOSOMAL ABNORMALITIES: A CASE REPORT,” ARCHIVES OF IRANIAN MEDICINE, vol. 21, no. 1, pp. 41–43, 2018, [Online]. Available: https://sid.ir/paper/281589/en

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