EFFECT OF DOUBLE IUI ON PREGNANCY RATE IN SUPEROVULATED CYCLES WITH CLOMIPHENE CITRATE

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KHADEM N.; RAFIE ZADEH ZH.

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Paper Information

Journal: Journal of Reproduction & Infertility Year:2003 | Volume:4 | Issue:4 (16) Page(s): 314-321

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Information Journal Paper

Title

EFFECT OF DOUBLE IUI ON PREGNANCY RATE IN SUPEROVULATED CYCLES WITH CLOMIPHENE CITRATE

Author(s)

KHADEM N. | RAFIE ZADEH ZH. | Issue Writer Certificate

Keywords

INTRAUTERINE INSEMINATION (IUI)Q3

SINGLE IUIQ3

DOUBLE JUIQ3

CLOMIPHENE CITRATEQ3

PREGNANCY RATEQ3

AND INFERTILITYQ2

Abstract

Infertility with an incidence of about 10- 1 5% is one of the community burdens that even threatens the continuity of the family life. Intrauterine insemination (IUI) is frequently used in the treatment of infertile couples with various causes of infertility. The difference PREGNANCY RATEs following a double IVI versus a single IVI has been reported. In this study we compared the effectiveness of double IVI before and after ovulation with a single IVI super ovulated cycles with CLOMIPHENE CITRATE. This was a prospective randomized controlled trial study. Our study was carried on 200 women with mild male factor without male factor infertility, and other female factor as an IVI candidate. They were stimulated with clomiphene 100 mg for 5 days plus HCG 10000 IV. On the day of HCG administration, patients were randomly divided into one of two groups; in group I, IVI was performed 36 hours after HCG injection and in group II, Double IVI was performed 18 and 42 hours after the HCG injection. Clinical PREGNANCY RATEs in both groups were compared per cycle. The demographic data for two groups were similar. PREGNANCY RATE of the first group was 14% versus 13% for the second group, so there was no statistical significance difference between two groups (double and single IVI) for the PREGNANCY RATEs in super ovulation cycles with CLOMIPHENE CITRATE. (P=0.834) The result of this study did not show benefit for double IVI over single IVI in CLOMIPHENE CITRATE/ HCG cycles. Regarding our Findings for future research in IVI candidate couple, using double IVI and comparing with single IVI especially with HMG/HCG super ovulation protocol and also infertile couple with male factor is suggested.

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APA: Copy

KHADEM, N., & RAFIE ZADEH, ZH.. (2003). EFFECT OF DOUBLE IUI ON PREGNANCY RATE IN SUPEROVULATED CYCLES WITH CLOMIPHENE CITRATE. JOURNAL OF REPRODUCTION AND INFERTILITY, 4(4 (16)), 314-321. SID. https://sid.ir/paper/28318/en

Vancouver: Copy

KHADEM N., RAFIE ZADEH ZH.. EFFECT OF DOUBLE IUI ON PREGNANCY RATE IN SUPEROVULATED CYCLES WITH CLOMIPHENE CITRATE. JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2003;4(4 (16)):314-321. Available from: https://sid.ir/paper/28318/en

IEEE: Copy

N. KHADEM, and ZH. RAFIE ZADEH, “EFFECT OF DOUBLE IUI ON PREGNANCY RATE IN SUPEROVULATED CYCLES WITH CLOMIPHENE CITRATE,” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 4, no. 4 (16), pp. 314–321, 2003, [Online]. Available: https://sid.ir/paper/28318/en

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