DOSIMETRY LIMITATIONS AND PRE-TREATMENT DOSE PROFILE CORRECTION FOR SLIDING WINDOW IMRT

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GRIGOROV G.; CHOW J.C.L.; YAZDANI N.

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Journal Paper

Paper Information

Journal: International Journal of Radiation Research Year:2010 | Volume:8 | Issue:2 Page(s): 61-74

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Information Journal Paper

Title

DOSIMETRY LIMITATIONS AND PRE-TREATMENT DOSE PROFILE CORRECTION FOR SLIDING WINDOW IMRT

Author(s)

GRIGOROV G. | CHOW J.C.L. | YAZDANI N. | Issue Writer Certificate

Keywords

IMRT

SLIDING WINDOW

PRE-TREATMENT QA AND PRE-TREATMENT DOSE CORRECTION

Abstract

Background: This work investigated the dosimetry limitations of the random and systematic uncertainties of SLIDING WINDOW (SW) intensity modulated radiation therapy (IMRT). Materials and Methods: A Varian 21EX linear accelerator, Pinnacle3 treatment planning system and radiographic film dosimetry was used. The limitations of the SW were studied using beam modulation ranging from 2 to 100 MU/beam, DR from 100 to 600 MU min-1, LV from 1 to 5 cm s-1 and field size up to 12 × 12 cm2. The random and systematic errors were investigated using clinical and flat beams, as well as beams of high profile modulation including linear, exponential, and sinusoidal profiles. Results: The leading edge and plateau of the SW profiles have a significant deformation for higher DR and for beams of < 10 MUs/beam. It was found that the error is directly proportional to the DR and LV, and inversely proportional to the number of MU/beam. Conclusion: The high DR and LV are limiting factors, producing random profile deformation when SW beams of small number of MU/beam are delivered. A very good agreement was found between the planned and delivered geometrical and clinical dose profiles when beams > 10 MUs irradiated by a DR from 100 to 600 MU min-1 and LV from 1 to 5 cm s-1. After the proposed correction, an average difference < 0.5% for clinical profiles was measured for beams irradiated with DR = 600 MU min-1 and LV= 5 cm s-1. It was concluded that this correction methodology may serve as a pre-treatment Quality Assurance tool for SW IMRT beams.

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APA: Copy

GRIGOROV, G., CHOW, J.C.L., & YAZDANI, N.. (2010). DOSIMETRY LIMITATIONS AND PRE-TREATMENT DOSE PROFILE CORRECTION FOR SLIDING WINDOW IMRT. INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 8(2), 61-74. SID. https://sid.ir/paper/286476/en

Vancouver: Copy

GRIGOROV G., CHOW J.C.L., YAZDANI N.. DOSIMETRY LIMITATIONS AND PRE-TREATMENT DOSE PROFILE CORRECTION FOR SLIDING WINDOW IMRT. INTERNATIONAL JOURNAL OF RADIATION RESEARCH[Internet]. 2010;8(2):61-74. Available from: https://sid.ir/paper/286476/en

IEEE: Copy

G. GRIGOROV, J.C.L. CHOW, and N. YAZDANI, “DOSIMETRY LIMITATIONS AND PRE-TREATMENT DOSE PROFILE CORRECTION FOR SLIDING WINDOW IMRT,” INTERNATIONAL JOURNAL OF RADIATION RESEARCH, vol. 8, no. 2, pp. 61–74, 2010, [Online]. Available: https://sid.ir/paper/286476/en

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