مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

284
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

219
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

POTENTIAL DRUG-DRUG INTERACTIONS IN POST-CCU OF A TEACHING HOSPITAL

Pages

  243-248

Abstract

 Drug-drug interactions (DDIs) can lead to increased toxicity or reduction in therapeuticefficacy. This study was designed to assess the incidence of potential DRUG INTERACTIONs (PDI) and rank their clinical value in post coronary care unit (POST-CCU) of a teaching hospital in Tehran, Iran.In this prospective study, three pharmacists with supervision of a clinical pharmacist actively gathered necessary information for detection of DDIs. Data were tabulated according to the combinations of drugs in treatment chart. Verification of potential DRUG INTERACTIONs was carried out using the online Lexi-InteractTM 2011.A total of 203 patients (113 males and 90 females) were enrolled in the study. The mean age of patients was 61 ± 12.55 years (range=26-93). A total of 90 drugs were prescribed to 203 patients and most prescribed drugs were atorvastatin, clopidogrel and metoprolol. Mean of drugs was 11.22 per patient. A total of 3166 potential DRUG INTERACTIONs have been identified by Lexi- InteractTM, 149 (4.71%) and 55 (1.73%) of which were categorized as D and X, respectively. The most serious interactions were clopidogrel+omeprazole and metoprolol+salbutamol.Drug interactions leading to serious adverse effects are to be cautiously watched for when multiple drugs are used simultaneously. In settings with multiple drug use attendance of apharmacist or clinical pharmacist, taking the responsibility for monitoring DRUG INTERACTIONs and notifying the physician about potential problems could decrease the harm in patient and increase the PATIENT SAFETY.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    HAJI AGHAJANI, MOHAMMAD, SISTANIZAD, MOHAMMAD, ABBASINAZARI, MOHAMMAD, ABIAR GHAMSARI, MAHDIEH, AYAZKHOO, LADAN, SAFI, OLIA, KAZEMI, KATAYOON, & KOUCHECK, MEHRAN. (2013). POTENTIAL DRUG-DRUG INTERACTIONS IN POST-CCU OF A TEACHING HOSPITAL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 12(1), 243-248. SID. https://sid.ir/paper/288094/en

    Vancouver: Copy

    HAJI AGHAJANI MOHAMMAD, SISTANIZAD MOHAMMAD, ABBASINAZARI MOHAMMAD, ABIAR GHAMSARI MAHDIEH, AYAZKHOO LADAN, SAFI OLIA, KAZEMI KATAYOON, KOUCHECK MEHRAN. POTENTIAL DRUG-DRUG INTERACTIONS IN POST-CCU OF A TEACHING HOSPITAL. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2013;12(1):243-248. Available from: https://sid.ir/paper/288094/en

    IEEE: Copy

    MOHAMMAD HAJI AGHAJANI, MOHAMMAD SISTANIZAD, MOHAMMAD ABBASINAZARI, MAHDIEH ABIAR GHAMSARI, LADAN AYAZKHOO, OLIA SAFI, KATAYOON KAZEMI, and MEHRAN KOUCHECK, “POTENTIAL DRUG-DRUG INTERACTIONS IN POST-CCU OF A TEACHING HOSPITAL,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 12, no. 1, pp. 243–248, 2013, [Online]. Available: https://sid.ir/paper/288094/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button