مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

COMPONENT ANALYSIS OF IRANIAN CRACK; A NEWLY ABUSED NARCOTIC SUBSTANCE IN IRAN

Pages

  337-344

Abstract

 Iranian CRACK is a new form of narcotic substance that has found widespread prevalence in Iran in the past years. CRACK only nominally resembles CRACK COCAINE/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> CRACK COCAINE as it is widely different in its clinical signs. Thus the present study aims to quantify the chemical combination of this drug. The samples included 18 specimen of CRACK collected from different zones of Tehran, Iran. All specimens were in the form of inodorous cream solid powdery substance. TLC and HPLC methods were used to perform semi-quantitative and quantitative analysis of the components, respectively.The TLC analysis showed no cocaine compound in the specimens while they all revealed to contain HEROIN, codeine, morphine and caffeine. All but two specimens contained thebaine. None of the specimens contained amphetamine, benzodiazepines, tricyclic antidepressants, aspirin, barbiturates, tramadol and buprenorphine. Acetaminophen was found in four specimens. HPLC revealed HEROIN to be the foundation substance in all specimens and most of them contained a significant amount of acetylcodeine. The present analysis of the chemical combination of CRACK showed that this substance is a HEROIN-based narcotic which is basically different from the cocaine-based CRACK used in Western countries. Studies like the present one at different time points, especially when abnormal clinical signs are detected, can reveal the chemical combination of the target substance and contribute to the clinical management of its acute or chronic poisoning.

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  • Cite

    APA: Copy

    FARHOUDIAN, ALI, SADEGHI, MANDANA, KHODDAMI VISHTEH, HAMID REZA, MOAZEN, BABAK, FEKRI, MONIR, & RAHIMI MOVAGHAR, AFARIN. (2014). COMPONENT ANALYSIS OF IRANIAN CRACK; A NEWLY ABUSED NARCOTIC SUBSTANCE IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 13(1), 337-344. SID. https://sid.ir/paper/288349/en

    Vancouver: Copy

    FARHOUDIAN ALI, SADEGHI MANDANA, KHODDAMI VISHTEH HAMID REZA, MOAZEN BABAK, FEKRI MONIR, RAHIMI MOVAGHAR AFARIN. COMPONENT ANALYSIS OF IRANIAN CRACK; A NEWLY ABUSED NARCOTIC SUBSTANCE IN IRAN. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2014;13(1):337-344. Available from: https://sid.ir/paper/288349/en

    IEEE: Copy

    ALI FARHOUDIAN, MANDANA SADEGHI, HAMID REZA KHODDAMI VISHTEH, BABAK MOAZEN, MONIR FEKRI, and AFARIN RAHIMI MOVAGHAR, “COMPONENT ANALYSIS OF IRANIAN CRACK; A NEWLY ABUSED NARCOTIC SUBSTANCE IN IRAN,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 13, no. 1, pp. 337–344, 2014, [Online]. Available: https://sid.ir/paper/288349/en

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